What Are The Essential Characteristics Of Serum PG In Chinese?
Pepsinogen (PG) is a precursor for pepsin, a digestive enzyme specifically produced in the gastric mucosa. Human PG can be classified into two different biochemical and immunological properties, PGI and PGII. Serum PG levels seem to be related to the morphologic and functional changes in the stomach, and used as "serological biopsy.
Insight Into Alzheimer's Disease Provided By Engineered Mice
One factor that determines how at risk an individual is of developing late-onset Alzheimer disease (AD) is the version of the APOE gene that they carry - those carrying the gene that enables them to make the apoE4 form of the apoE protein are at increased risk and those carrying the gene that enables them to make the apoE2 form are at decreased risk.
Indian Medicinal Plant Acanthus Ilicifolius May Combat Liver Cancer
Liver cancer is the fifth most common cancer in the world with a poor prognosis. About three quarters of the cases of liver cancer are found in Southeast Asia, including China, Hong Kong, Taiwan, Korea, India, and Japan. The frequency of liver cancer in Southeast Asia and sub-Saharan Africa is greater than 20 cases per 100,000 population. Moreover, recent data show the frequency of liver cancer in the U.S. overall is rising.
Sunday, January 20, 2008
Beyond The Abstract - The Value Of Combined Use Of Survivin, Cytokeratin 20 And Mucin 7 MRNA For Bladder Cancer Detection In Voided Urine
Beyond The Abstract - The Value Of Combined Use Of Survivin, Cytokeratin 20 And Mucin 7 MRNA For Bladder Cancer Detection In Voided Urine
UroToday.com - This study analyzed the clinical value of combined use of survivin, cytokeratin (CK) 20, and mucin (MUC) 7 mRNA in the detection of bladder cancer patients in China. The group evaluated these three markers in voided urine using traditional RT-PCR. It is confirmed that the overall sensitivity and specificity of the three markers were all higher than voided urine cytology.
Beyond The Abstract - P53 Gene And Protein Status: The Role Of P53 Alterations In Predicting Outcome In Patients With Bladder Cancer
UroToday.com - The function of the normal product of the TP53 gene, the p53 protein, forms the crucial basis of normal cell biology; conversely, the dysfunction of its mutant protein product underlies altered cellular response in cancer. One reason why the protein accumulates in human tumors is that wild-type p53 has a very short half-life (approximately 20 to 30 minutes), whereas mutant p53 proteins often have a much longer half-life (approximately 24 hours).
Beyond The Abstract - Sequential Bilateral Minimum Incision Endoscopic Radical Nephrectomy In Dialysis Patients With Bilateral Renal Cell Carcinomas
UroToday.com - Renal cell carcinoma (RCC) occurs in dialysis patients more frequent than the general non-dialyzed population. RCC in dialysis patients can often be multiple and sometimes occurs bilaterally. Dialysis patients often have poor physical status because of multiple complications such as respiratory or cardiac problems in addition to chronic renal failure (CRF).
UroToday.com - This study analyzed the clinical value of combined use of survivin, cytokeratin (CK) 20, and mucin (MUC) 7 mRNA in the detection of bladder cancer patients in China. The group evaluated these three markers in voided urine using traditional RT-PCR. It is confirmed that the overall sensitivity and specificity of the three markers were all higher than voided urine cytology.
Beyond The Abstract - P53 Gene And Protein Status: The Role Of P53 Alterations In Predicting Outcome In Patients With Bladder Cancer
UroToday.com - The function of the normal product of the TP53 gene, the p53 protein, forms the crucial basis of normal cell biology; conversely, the dysfunction of its mutant protein product underlies altered cellular response in cancer. One reason why the protein accumulates in human tumors is that wild-type p53 has a very short half-life (approximately 20 to 30 minutes), whereas mutant p53 proteins often have a much longer half-life (approximately 24 hours).
Beyond The Abstract - Sequential Bilateral Minimum Incision Endoscopic Radical Nephrectomy In Dialysis Patients With Bilateral Renal Cell Carcinomas
UroToday.com - Renal cell carcinoma (RCC) occurs in dialysis patients more frequent than the general non-dialyzed population. RCC in dialysis patients can often be multiple and sometimes occurs bilaterally. Dialysis patients often have poor physical status because of multiple complications such as respiratory or cardiac problems in addition to chronic renal failure (CRF).
Saturday, January 19, 2008
First Two Cases Of XDR-TB Confirmed In Botswana, Ministry Of Health Say
First Two Cases Of XDR-TB Confirmed In Botswana, Ministry Of Health Say
Botswana's Ministry of Health on Wednesday said it has confirmed the country's first two cases of extensively drug-resistant tuberculosis, which is resistant to the two most potent first-line treatments and some of the available second-line drugs, the AP/Google.com reports.
EPIX Pharmaceuticals Announces Updated Results From Phase 2a Clinical Trial Of PRX-03140 In Alzheimer's Disease
EPIX Pharmaceuticals, Inc. (NASDAQ:EPIX), a biopharmaceutical company focused on discovering and developing novel therapeutics through the use of its proprietary and highly efficient in silico drug discovery platform, today announced revised results from its Phase 2a clinical trial of PRX-03140, its novel 5-HT4 agonist, in Alzheimer's disease.
Scientists Discover Virus Linked To Deadly Skin Cancer
A new way of searching for human viruses has helped scientists at the University of Pittsburgh Cancer Institute in the US find a previously unknown one that is linked to a deadly form of skin cancer called Merkel cell carcinoma (MCC).
Abbott Announces Approval Of First Fully Automated Blood Screening Test For HTLV-I/HTLV-II
Abbott (NYSE: ABT) announced it received approval from the U.S. Food and Drug Administration for its fully automated HTLV-I/HTLV-II blood screening test for use on the ABBOTT PRISM instrument. The test is intended for use by laboratories to screen individual donations of blood and plasma for antibodies to human T -- lymphotropic virus Type I and/or human T -- lymphotropic virus Type II (anti-HTLV-I/HTLV-II).
Can Hantavirus Infection Spread Among Humans?
In connection with last year's epidemic, a research team at Umeå University in Sweden has managed for the first time to show that hantavirus exists in human saliva. This raises the question of whether this contagion can spread among humans.In Sweden, a form of hemorrhagic fever with renal syndrome called nephropathia epidemica occurs primarily in the northern parts of the country.
A Tricky Tumor Virus: Epstein-Barr Virus Reprograms The Biological Properties Of A Signal Protein Of Its Host Cells
Viruses use many tricks to gain control over their host cells and to reprogram them to their own advantage. Dr. Arnd Kieser and his colleagues of the Department of Gene Vectors of the Helmholtz Zentrum München, Germany, were able to show in a recent publication in PloS Biology by which mechanism Epstein-Barr virus exploits a signal protein of its host cell, which normally mediates programmed cell death (apoptosis), in order to convert the cell into a cancer cell.
Botswana's Ministry of Health on Wednesday said it has confirmed the country's first two cases of extensively drug-resistant tuberculosis, which is resistant to the two most potent first-line treatments and some of the available second-line drugs, the AP/Google.com reports.
EPIX Pharmaceuticals Announces Updated Results From Phase 2a Clinical Trial Of PRX-03140 In Alzheimer's Disease
EPIX Pharmaceuticals, Inc. (NASDAQ:EPIX), a biopharmaceutical company focused on discovering and developing novel therapeutics through the use of its proprietary and highly efficient in silico drug discovery platform, today announced revised results from its Phase 2a clinical trial of PRX-03140, its novel 5-HT4 agonist, in Alzheimer's disease.
Scientists Discover Virus Linked To Deadly Skin Cancer
A new way of searching for human viruses has helped scientists at the University of Pittsburgh Cancer Institute in the US find a previously unknown one that is linked to a deadly form of skin cancer called Merkel cell carcinoma (MCC).
Abbott Announces Approval Of First Fully Automated Blood Screening Test For HTLV-I/HTLV-II
Abbott (NYSE: ABT) announced it received approval from the U.S. Food and Drug Administration for its fully automated HTLV-I/HTLV-II blood screening test for use on the ABBOTT PRISM instrument. The test is intended for use by laboratories to screen individual donations of blood and plasma for antibodies to human T -- lymphotropic virus Type I and/or human T -- lymphotropic virus Type II (anti-HTLV-I/HTLV-II).
Can Hantavirus Infection Spread Among Humans?
In connection with last year's epidemic, a research team at Umeå University in Sweden has managed for the first time to show that hantavirus exists in human saliva. This raises the question of whether this contagion can spread among humans.In Sweden, a form of hemorrhagic fever with renal syndrome called nephropathia epidemica occurs primarily in the northern parts of the country.
A Tricky Tumor Virus: Epstein-Barr Virus Reprograms The Biological Properties Of A Signal Protein Of Its Host Cells
Viruses use many tricks to gain control over their host cells and to reprogram them to their own advantage. Dr. Arnd Kieser and his colleagues of the Department of Gene Vectors of the Helmholtz Zentrum München, Germany, were able to show in a recent publication in PloS Biology by which mechanism Epstein-Barr virus exploits a signal protein of its host cell, which normally mediates programmed cell death (apoptosis), in order to convert the cell into a cancer cell.
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