Monday, December 15, 2008

Allergists Respond To FDA Committee Recommendation On Asthma Medication, Encourage Patients With Questions To Contact Physicians

The nation's allergists urged a Joint FDA Advisory Committee today to continue to make long-acting beta-2 agonists available for the treatment of moderate-to-severe asthma in appropriate patients. More at...

IDO2 An Active Enzyme To Target In Pancreatic Cancer

An enzyme that is overexpressed in pancreatic cancer cells may hold the key to successfully treating the disease with targeted immunotherapy, researchers from Thomas Jefferson University reported at the 2008 Annual Meeting of the Southern Surgical Association.

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A University of Iowa study provides insight into a calcium-sensing enzyme already known to play a role in irregular heartbeats and other critical functions. The researchers showed that the enzyme, calmodulin kinase II (CaM kinase II), contributes to arrhythmia in an extremely rare disease called Timothy syndrome and that inhibiting the enzyme prevents irregular heartbeats.

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One in 35 people with colon cancer carry a hereditary form of the disease, according to the second of two studies led by researchers at The Ohio State University Comprehensive Cancer Center.

Based on the finding, researchers recommend screening all colon-cancer patients for Lynch syndrome, the most common inherited form of colon cancer.

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A UCLA study shows for the first time how microscopic crystals form sound and gravity sensors inside the inner ear. Located at the ends of cilia — tiny cellular hairs in the ear that move and transmit signals — these crystals play an important role in detecting sound, maintaining balance and regulating movement.

Dislodged ear crystals are to blame for the most common form of vertigo. Known as benign paroxysmal positional vertigo, the disorder plagues up to 10 percent of people older than 60 and causes 20 percent of patients' dizziness complaints.

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A University of Iowa researcher and colleagues at the University of Michigan have discovered a direct link between disruption of a critical cellular housekeeping process and fatty liver disease, a condition that causes fat to accumulate in the liver.

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A novel angled gantry approach to coronary CT angiography reduced radiation exposure to the breast by more than 50%, according to Thomas Jefferson University researchers.

Ethan Halpern, M.D., associate professor of Radiology at Jefferson Medical College of Thomas Jefferson University in Philadelphia, presented the research at the 94th Scientific Assembly and Annual Meeting of the Radiological Society of North America.

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An automated system worked well in helping manage routine chemotherapy side effects in women with metastatic breast cancer, according to research conducted in part at Beaumont Hospital in Royal Oak.

One hundred ninety-four women with an average age of 50 were assessed on 15 symptoms ranging from anxiety to fatigue. Half were randomly assigned to an automated system.

Patients received weekly phone calls for the first four weeks, were called during week six and received a final call during week eight. More than 85 percent of the participants completed the study.

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