A second cholera outbreak has hit Chegutu, a town 100 km west of Harare, where more than 100 people have died since the first cases appeared on November 24. MSF arrived in Chegutu, which has a population of 55,000, on December 12 after being told that day of the cholera emergency there. The scene MSF found at the town's small government cholera treatment center (CTC) was grim. Read more ...
The Ministry of Health (MoH) of the Democratic Republic of the Congo declared on 25 December an outbreak of Ebola haemorrhagic fever in Mweka District, Kasai Occidental province based on laboratory results from the Centre International de Recherches Médicales de Franceville (CIRMF) in Gabon. CIRMF confirmed the presence of Ebola virus in 2 samples from 2 of the patients in the outbreak by antigen detection. Read more ...
Scientists in Japan are reporting an advance toward using a natural disease-fighting protein in pills or syrups that patients can take by mouth rather than injection. Their study is the first to show that coating the protein with a polymer material already in wide medical use can increase its absorption by the intestine. The research appears in the current issue of ACS' Bioconjugate Chemistry, a monthly journal. Read more ...
Wednesday, December 31, 2008
Monday, December 29, 2008
Two Cardiovascular Proteins Pose A Double Whammy In Alzheimer's
Researchers have found that two proteins which work in tandem in the brain's blood vessels present a double whammy in Alzheimer's disease. Not only do the proteins lessen blood flow in the brain, but they also reduce the rate at which the brain is able to remove amyloid beta, the protein that builds up in toxic quantities in the brains of patients with the disease. The work, described in a paper published online Dec. Read more ...
Sunday, December 28, 2008
News From The Journals Of The American Society For Microbiology
News From The Journals Of The American Society For Microbiology
Killer Peptide May Offer New Therapy Against Influenza A Virus In a new study researchers identified what appears to be the first antibody-derived peptide that inhibits the activities of harmful microbes such as influenza A virus and HIV-1. They report their findings in the December 2008 issue of the journal Antimicrobial Agents and Chemotherapy.
Killer Peptide May Offer New Therapy Against Influenza A Virus In a new study researchers identified what appears to be the first antibody-derived peptide that inhibits the activities of harmful microbes such as influenza A virus and HIV-1. They report their findings in the December 2008 issue of the journal Antimicrobial Agents and Chemotherapy.
Saturday, December 27, 2008
Horseback Riding: Impact On Sexual Dysfunction And Lower Urinary Tract Symptoms In Men And Women
Horseback Riding: Impact On Sexual Dysfunction And Lower Urinary Tract Symptoms In Men And Women
Does Persistent Perineal Impact Increase Likelihood of LUTS and Sexual Dysfunction? UroToday.com - Bicycle riding has been reported to be related to male sexual dysfunction. Dr. Shaheen Alanee and colleagues from Minneapolis hypothesized that similar force impacts might be seen in equestrian sports. They sought to evaluate the effect of horseback riding on urinary symptoms and sexual dysfunction in men and women. Swimmers were used as a control group.
Does Persistent Perineal Impact Increase Likelihood of LUTS and Sexual Dysfunction? UroToday.com - Bicycle riding has been reported to be related to male sexual dysfunction. Dr. Shaheen Alanee and colleagues from Minneapolis hypothesized that similar force impacts might be seen in equestrian sports. They sought to evaluate the effect of horseback riding on urinary symptoms and sexual dysfunction in men and women. Swimmers were used as a control group.
Friday, December 26, 2008
Research finds the area of brain key to choosing words
New research by a Rice University psychologist clearly identifies the parts of the brain involved in the process of choosing appropriate words during speech.
The study, published in the current issue of the Proceedings of the National Academy of Sciences, could help researchers better understand the speech problems that stroke patients experience.
Complete news at...Thursday, December 25, 2008
Memory Pharmaceuticals Reports Phase 1 Data For R4996/MEM 63908
Memory Pharmaceuticals Reports Phase 1 Data For R4996/MEM 63908
Memory Pharmaceuticals Corp. (Nasdaq: MEMY) announced positive results from its Phase 1 program for R4996/MEM 63908, a partial agonist of the nicotinic alpha-7 receptor being developed in collaboration with Roche for cognitive disorders such as Alzheimer's disease. The Phase 1 program enrolled over 130 subjects and included a single-ascending dose study, a food interaction study, a study in elderly volunteers and a multiple ascending dose study.
In Early Diagnosis Of Alzheimer's Disease, MRI Brain Scans Accurate
MRI scans that detect shrinkage in specific regions of the mid-brain attacked by Alzheimer's disease accurately diagnose the neurodegenerative disease, even before symptoms interfere with daily function, a study by the Florida Alzheimer's Disease Research Center (ADRC) in Miami and Tampa found.
Memory Pharmaceuticals Corp. (Nasdaq: MEMY) announced positive results from its Phase 1 program for R4996/MEM 63908, a partial agonist of the nicotinic alpha-7 receptor being developed in collaboration with Roche for cognitive disorders such as Alzheimer's disease. The Phase 1 program enrolled over 130 subjects and included a single-ascending dose study, a food interaction study, a study in elderly volunteers and a multiple ascending dose study.
In Early Diagnosis Of Alzheimer's Disease, MRI Brain Scans Accurate
MRI scans that detect shrinkage in specific regions of the mid-brain attacked by Alzheimer's disease accurately diagnose the neurodegenerative disease, even before symptoms interfere with daily function, a study by the Florida Alzheimer's Disease Research Center (ADRC) in Miami and Tampa found.
Wednesday, December 24, 2008
MRSA Infections Continue To Fall, UK
MRSA Infections Continue To Fall, UK
MRSA bloodstream infections in England are continuing to fall, the latest quarterly statistics from the Health Protection Agency (HPA) showed today. There were 725 MRSA bloodstream infections in England between July and September. This represents a 13% decrease on the previous quarter (April to June) when there were 837 cases and a 33% reduction in the corresponding quarter of 2007.
Type 1 Diabetes May Be Triggered By Common Infant Virus
Human parechovirus is a harmless virus which is encountered by most infants and displays few symptoms. Suspected of triggering type 1 diabetes in susceptible people, research methods need to take this "silent" virus into consideration. This comes from findings in a study from the Norwegian Institute of Public Health. This study was part of a long-term project at the Norwegian Institute of Public Health to investigate if environmental risk factors affect type 1 diabetes.
VLST Corporation And Novo Nordisk Announce Collaboration Agreement To Develop Therapeutics For Autoimmune And Inflammatory Disorders
Novo Nordisk and VLST Corporation, a Seattle-based biotechnology company focused on the development of therapeutics for autoimmune and inflammatory disorders, announced that the companies have entered into an exclusive, worldwide collaboration agreement to develop therapeutic targets utilizing VLST's technology platform in the fields of autoimmune and inflammatory disorders.
Practice Food Safety To Prevent Food-Borne Illness During Holidays
Food safety is important year round but a state health official reminds South Dakotans to pay particular attention as they entertain family and friends at holiday gatherings. "Bacterial food-borne illness, more commonly called food poisoning, can be prevented with common sense measures such as thorough hand washing, cooking and storing foods at the proper temperature, and avoiding food preparation when you're sick," said Dr.
LSUHSC's Hill Selected As Fellow Of AAAS
James M. Hill, PhD, Professor of Ophthalmology, Pharmacology, Microbiology, and Neuroscience at the LSU Health Sciences Center New Orleans School of Medicine, has been awarded the distinction of American Association for the Advancement of Science (AAAS) Fellow. Election as a Fellow is an honor bestowed upon AAAS members by their peers. Dr.
E. coli In The Urinary Tract
Transfer of information is a basic property of biological systems. Common examples include transfer of genetic information or nerve impulses Transmission of signals occurs at an even more fundamental level between and within cells, including signaling molecules, which bear a phosphate or a sulfate group. The latter contain a sulfur atom.
Blocking The Spread Of Antibiotic Resistance In Bacteria
It's as simple as A, T, G, C. Northwestern University scientists have exploited the Watson-Crick base pairing of DNA to provide a defensive tool that could be used to fight the spread of antibiotic resistance in bacteria - one of the world's most pressing public health problems. The resistant nasty pathogens cause thousands of deaths each year in the United States.
MRSA bloodstream infections in England are continuing to fall, the latest quarterly statistics from the Health Protection Agency (HPA) showed today. There were 725 MRSA bloodstream infections in England between July and September. This represents a 13% decrease on the previous quarter (April to June) when there were 837 cases and a 33% reduction in the corresponding quarter of 2007.
Type 1 Diabetes May Be Triggered By Common Infant Virus
Human parechovirus is a harmless virus which is encountered by most infants and displays few symptoms. Suspected of triggering type 1 diabetes in susceptible people, research methods need to take this "silent" virus into consideration. This comes from findings in a study from the Norwegian Institute of Public Health. This study was part of a long-term project at the Norwegian Institute of Public Health to investigate if environmental risk factors affect type 1 diabetes.
VLST Corporation And Novo Nordisk Announce Collaboration Agreement To Develop Therapeutics For Autoimmune And Inflammatory Disorders
Novo Nordisk and VLST Corporation, a Seattle-based biotechnology company focused on the development of therapeutics for autoimmune and inflammatory disorders, announced that the companies have entered into an exclusive, worldwide collaboration agreement to develop therapeutic targets utilizing VLST's technology platform in the fields of autoimmune and inflammatory disorders.
Practice Food Safety To Prevent Food-Borne Illness During Holidays
Food safety is important year round but a state health official reminds South Dakotans to pay particular attention as they entertain family and friends at holiday gatherings. "Bacterial food-borne illness, more commonly called food poisoning, can be prevented with common sense measures such as thorough hand washing, cooking and storing foods at the proper temperature, and avoiding food preparation when you're sick," said Dr.
LSUHSC's Hill Selected As Fellow Of AAAS
James M. Hill, PhD, Professor of Ophthalmology, Pharmacology, Microbiology, and Neuroscience at the LSU Health Sciences Center New Orleans School of Medicine, has been awarded the distinction of American Association for the Advancement of Science (AAAS) Fellow. Election as a Fellow is an honor bestowed upon AAAS members by their peers. Dr.
E. coli In The Urinary Tract
Transfer of information is a basic property of biological systems. Common examples include transfer of genetic information or nerve impulses Transmission of signals occurs at an even more fundamental level between and within cells, including signaling molecules, which bear a phosphate or a sulfate group. The latter contain a sulfur atom.
Blocking The Spread Of Antibiotic Resistance In Bacteria
It's as simple as A, T, G, C. Northwestern University scientists have exploited the Watson-Crick base pairing of DNA to provide a defensive tool that could be used to fight the spread of antibiotic resistance in bacteria - one of the world's most pressing public health problems. The resistant nasty pathogens cause thousands of deaths each year in the United States.
Tuesday, December 23, 2008
New Interventions Added to the Updated Compendium of Evidence-Based Interventions
The ongoing PRS efficacy review process has identified 57 evidence-based HIV behavioral interventions (as of May 2008). On December 19, 2008, eight new intervention fact sheets were added. Read more ...
Monday, December 22, 2008
Drug That Counteracts The Effects Of Leptin May Benefit Cardiac Stent Patients With Diabetes
Drug That Counteracts The Effects Of Leptin May Benefit Cardiac Stent Patients With Diabetes
The naturally high levels of leptin in diabetic patients may reduce the effectiveness of drug-eluting stents used to treat heart blockages, but using a chemical that differs from the one commonly used to coat stents could counteract this effect. The work by researchers at Columbia University Medical Center could potentially improve outcomes in diabetics who get stents, they say.
Study Shows Regular Exercise Might Prevent Onset Of Diabetes In Black Women
Taking a brisk walk several times a week for exercise appears to reduce black women's risk of developing type 2 diabetes, according to a study published this month in the American Journal of Epidemiology, Reuters Health reports. Few studies have been conducted on the benefits of exercise among black women, according to Reuters.
Updated Fact Sheet: Male Latex Condoms and Sexually Transmitted Diseases
This fact sheet presents evidence concerning the male latex condom and the prevention of STDs, including HIV, based on information about how different STDs are transmitted, the physical properties of condoms, the anatomic coverage or protection that condoms provide, and epidemiologic studies assessing condom use and STD risk.
Putting Heart Into Diabetes And Coronary Care
A quarter of Type 2 diabetes patients admitted to hospital with a heart problem were readmitted within 28 days, compared to just six per cent of coronary patients who did not have diabetes, a Queensland University of Technology researcher has found. Dr Jo Wu, from the School of Nursing, discovered during her latest study that people who have diabetes and a heart condition often find it difficult to manage both conditions, leading to a high number of hospital readmissions.
The naturally high levels of leptin in diabetic patients may reduce the effectiveness of drug-eluting stents used to treat heart blockages, but using a chemical that differs from the one commonly used to coat stents could counteract this effect. The work by researchers at Columbia University Medical Center could potentially improve outcomes in diabetics who get stents, they say.
Study Shows Regular Exercise Might Prevent Onset Of Diabetes In Black Women
Taking a brisk walk several times a week for exercise appears to reduce black women's risk of developing type 2 diabetes, according to a study published this month in the American Journal of Epidemiology, Reuters Health reports. Few studies have been conducted on the benefits of exercise among black women, according to Reuters.
Updated Fact Sheet: Male Latex Condoms and Sexually Transmitted Diseases
This fact sheet presents evidence concerning the male latex condom and the prevention of STDs, including HIV, based on information about how different STDs are transmitted, the physical properties of condoms, the anatomic coverage or protection that condoms provide, and epidemiologic studies assessing condom use and STD risk.
Putting Heart Into Diabetes And Coronary Care
A quarter of Type 2 diabetes patients admitted to hospital with a heart problem were readmitted within 28 days, compared to just six per cent of coronary patients who did not have diabetes, a Queensland University of Technology researcher has found. Dr Jo Wu, from the School of Nursing, discovered during her latest study that people who have diabetes and a heart condition often find it difficult to manage both conditions, leading to a high number of hospital readmissions.
Saturday, December 20, 2008
Extra-Virgin Olive Oil Has Anti-Cancer Components
Extra-Virgin Olive Oil Has Anti-Cancer Components
Good quality extra-virgin olive oil contains health-relevant chemicals, 'phytochemicals', that can trigger cancer cell death. New research published in the open access journal BMC Cancer sheds more light on the suspected association between olive oil-rich Mediterranean diets and reductions in breast cancer risk.
Medical Alliance Pays Off-Collaboration Leads To Expanded Research Opportunities
A vast resource of information critical to cancer research is now leading to new opportunities for scientists - information that could lead to improved cancer treatments. The collaboration known as the Huntsman-Intermountain Cancer Care Program is now yielding data that can be used for studies relating to genetics, health services and public health.
Good quality extra-virgin olive oil contains health-relevant chemicals, 'phytochemicals', that can trigger cancer cell death. New research published in the open access journal BMC Cancer sheds more light on the suspected association between olive oil-rich Mediterranean diets and reductions in breast cancer risk.
Medical Alliance Pays Off-Collaboration Leads To Expanded Research Opportunities
A vast resource of information critical to cancer research is now leading to new opportunities for scientists - information that could lead to improved cancer treatments. The collaboration known as the Huntsman-Intermountain Cancer Care Program is now yielding data that can be used for studies relating to genetics, health services and public health.
In Juvenile Diabetes Metabolic Disturbances Indicate Progress Of The Disease Even Years In Advance
Finnish scientists have reported a breakthrough in the attempts to understand the development of type 1 diabetes. They discovered disturbances in lipid and amino acid metabolism in children who later progressed to type 1 diabetes, also known as juvenile diabetes. The alterations preceded the autoimmune response by months to years. The study may prompt new approaches for prediction and prevention of type 1 diabetes in pre-autoimmune phase of the disease. Complete news at...
Friday, December 19, 2008
Addex Starts A Second Phase IIb Trial Of ADX10059 In GERD
Addex Pharmaceuticals (SWISS: ADXN), the allosteric modulation company, announced the start of a Phase IIb trial of ADX10059 monotherapy in patients with gastroesophageal reflux disease (GERD), the cause of heartburn and other symptoms. ADX10059 is a first-in- class reflux inhibitor that works by reducing activation of the metabotropic glutamate receptor 5 (mGluR5) through negative allosteric modulation (NAM). Read more ...
The HIV/AIDS Surveillance Supplemental Report is published by the Division of HIV/AIDS Prevention, National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention, Coordinating Center for Infectious Diseases, Centers for Disease Control and Prevention (CDC), U.S. Department of Health and Human Services, Atlanta, Georgia. Read more ...
The HIV/AIDS Surveillance Supplemental Report is published by the Division of HIV/AIDS Prevention, National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention, Coordinating Center for Infectious Diseases, Centers for Disease Control and Prevention (CDC), U.S. Department of Health and Human Services, Atlanta, Georgia. Read more ...
Annual Congress European Association Of Urology: Highlights In Stockholm
The 24th Annual Congress of the European Association of Urology (EAU) will be held from 17 to 21 March 2009 in the Stockholm International Fairs (SE). The scientific programme covers the whole range of the urological field. From 'Bladder Unlimited' to 'The art of ageing'; it will all be discussed at the congress. The traditional half-day joint sessions with regional urological groups are extended to a full-day event called EAU International Day - Urology Beyond Europe. More at...
Family and friends of a 75-year-old California grandmother beaten and kidnapped from her home last week might have known of the crime within moments if a device patented by an Indiana University researcher had been in use. If Sandy Vinge had been using The Portal Monitor developed by Indiana University professor L. More at...
Sorafenib significantly increases overall survival in Asian-Pacific patients with advanced hepatocellular carcinoma - a group where surgical treatments can be limited - according to findings of a phase III trial reported in an Article published early Online and in the January edition of The Lancet Oncology. Hepatocellular carcinoma is the third most common cause of cancer-related death and is a particular challenge in the Asia-Pacific region, where 75% of cases occur. More at...
Elsevier, world-leading publisher of scientific, technical, and medical information products and services, is pleased to announce that, beginning in January 2009, the internationally respected Journal of Pain and Symptom Management (JPSM) (http://www.jpsmjournal.com) will be the official journal of the American Academy of Hospice and Palliative Medicine (AAHPM). More at...
Family and friends of a 75-year-old California grandmother beaten and kidnapped from her home last week might have known of the crime within moments if a device patented by an Indiana University researcher had been in use. If Sandy Vinge had been using The Portal Monitor developed by Indiana University professor L. More at...
Sorafenib significantly increases overall survival in Asian-Pacific patients with advanced hepatocellular carcinoma - a group where surgical treatments can be limited - according to findings of a phase III trial reported in an Article published early Online and in the January edition of The Lancet Oncology. Hepatocellular carcinoma is the third most common cause of cancer-related death and is a particular challenge in the Asia-Pacific region, where 75% of cases occur. More at...
Elsevier, world-leading publisher of scientific, technical, and medical information products and services, is pleased to announce that, beginning in January 2009, the internationally respected Journal of Pain and Symptom Management (JPSM) (http://www.jpsmjournal.com) will be the official journal of the American Academy of Hospice and Palliative Medicine (AAHPM). More at...
Thursday, December 18, 2008
Scientists Fool Bacteria Into Killing Themselves To Survive
Like firemen fighting fire with fire, researchers at the University of Illinois and the University of Massachusetts at Amherst have found a way to fool a bacteria's evolutionary machinery into programming its own death. Continue reading ...
MIT researchers have found that the pigments responsible for the blue-green stain of the mucus that clogs the lungs of cystic fibrosis (CF) patients are primarily signaling molecules that allow large clusters of the opportunistic infection agent, Pseudomonas aeruginosa, to organize themselves into structured communities. Continue reading ...
Management of Clostridium difficileinfection (CDI) in geriatric and pediatric populations can be challenging and complicated. Because of the observed increase in CDI incidence in many age groups, healthcare professionals need to be especially attuned to the individual needs of these patient populations. Continue reading ...
Evolving HIV viral strains and the adverse side effects associated with long-term exposure to current treatments propel scientists to continue exploring alternative HIV treatments. In a new study, a University of Missouri researcher has identified broad-spectrum aptamers. Aptamers are synthetic molecules that prevent the HIV virus from reproducing. Continue reading ...
ACCESS PHARMACEUTICALS, INC. (OTC Bulletin Board: ACCP) and MACROCHEM CORPORATION (OTC Bulletin Board: MACM) announced that the results of two Phase 3 studies of pexiganan for the topical treatment of mild diabetic foot infection were published in the December 15, 2008 issue of Clinical Infectious Diseases. The publication was authored by Benjamin A. Lipsky, M.D. Continue reading ...
MIT researchers have found that the pigments responsible for the blue-green stain of the mucus that clogs the lungs of cystic fibrosis (CF) patients are primarily signaling molecules that allow large clusters of the opportunistic infection agent, Pseudomonas aeruginosa, to organize themselves into structured communities. Continue reading ...
Management of Clostridium difficileinfection (CDI) in geriatric and pediatric populations can be challenging and complicated. Because of the observed increase in CDI incidence in many age groups, healthcare professionals need to be especially attuned to the individual needs of these patient populations. Continue reading ...
Evolving HIV viral strains and the adverse side effects associated with long-term exposure to current treatments propel scientists to continue exploring alternative HIV treatments. In a new study, a University of Missouri researcher has identified broad-spectrum aptamers. Aptamers are synthetic molecules that prevent the HIV virus from reproducing. Continue reading ...
ACCESS PHARMACEUTICALS, INC. (OTC Bulletin Board: ACCP) and MACROCHEM CORPORATION (OTC Bulletin Board: MACM) announced that the results of two Phase 3 studies of pexiganan for the topical treatment of mild diabetic foot infection were published in the December 15, 2008 issue of Clinical Infectious Diseases. The publication was authored by Benjamin A. Lipsky, M.D. Continue reading ...
Cognitive Function May Be Affected By High Blood Pressure In The Elderly
Adding another reason for people to watch their blood pressure, a new study from North Carolina State University shows that increased blood pressure in older adults is directly related to decreased cognitive functioning, particularly among seniors with already high blood pressure. This means that stressful situations may make it more difficult for some seniors to think clearly. Dr. Continue reading ...
Australian scientists at CSIRO (Commonwealth Scientific and Industrial Research Organisation), have developed a new system to screen for compounds that can inhibit one of the processes that takes place during the progression of Alzheimer's disease. In a paper published in the November issue of the Journal of Alzheimer's Disease, folate is shown to be beneficial in the screening system. Continue reading ...
Abbott (NYSE: ABT) announced the start of SPIRIT Small Vessel, a clinical trial evaluating a 2.25 mm size of the XIENCE V(TM) Everolimus Eluting Coronary Stent System. The 2.25 mm stent system would offer physicians an option for treating coronary artery disease in narrower vessels that is based on the proven efficacy, safety and deliverability of XIENCE V. Continue reading ...
Lantheus Medical Imaging, Inc. a worldwide leader in diagnostic imaging, announced today new data from a retrospective, multicenter, cohort study of over four million hospitalized patients that shows similar unadjusted mortality rates for patients receiving DEFINITY Vial For (Perflutren Lipid Microsphere) Injectable Suspension enhanced resting echocardiography exams when compared with patients who did not receive DEFINITY. Continue reading ...
There are 700,000 people in the UK currently living with dementia. This number is expected to double by 2019, with 163,000 new cases of dementia occurring in England and Wales each year. In total, 42% of the UK population are affected by dementia - by way of knowing a close friend or family member with the condition. Continue reading ...
Very few species spontaneously develop the cognitive, behavioral and neuropathological symptoms of Alzheimer's disease (AD), yet AD research must progress at a more rapid pace than the rate of human aging. Therefore, in recent years, a variety of animal models have been created - from tiny invertebrates with life spans measurable in months to huge mammals that live several decades. Continue reading ...
Australian scientists at CSIRO (Commonwealth Scientific and Industrial Research Organisation), have developed a new system to screen for compounds that can inhibit one of the processes that takes place during the progression of Alzheimer's disease. In a paper published in the November issue of the Journal of Alzheimer's Disease, folate is shown to be beneficial in the screening system. Continue reading ...
Abbott (NYSE: ABT) announced the start of SPIRIT Small Vessel, a clinical trial evaluating a 2.25 mm size of the XIENCE V(TM) Everolimus Eluting Coronary Stent System. The 2.25 mm stent system would offer physicians an option for treating coronary artery disease in narrower vessels that is based on the proven efficacy, safety and deliverability of XIENCE V. Continue reading ...
Lantheus Medical Imaging, Inc. a worldwide leader in diagnostic imaging, announced today new data from a retrospective, multicenter, cohort study of over four million hospitalized patients that shows similar unadjusted mortality rates for patients receiving DEFINITY Vial For (Perflutren Lipid Microsphere) Injectable Suspension enhanced resting echocardiography exams when compared with patients who did not receive DEFINITY. Continue reading ...
There are 700,000 people in the UK currently living with dementia. This number is expected to double by 2019, with 163,000 new cases of dementia occurring in England and Wales each year. In total, 42% of the UK population are affected by dementia - by way of knowing a close friend or family member with the condition. Continue reading ...
Very few species spontaneously develop the cognitive, behavioral and neuropathological symptoms of Alzheimer's disease (AD), yet AD research must progress at a more rapid pace than the rate of human aging. Therefore, in recent years, a variety of animal models have been created - from tiny invertebrates with life spans measurable in months to huge mammals that live several decades. Continue reading ...
Wednesday, December 17, 2008
WHO Update Of Avian Influenza Situation In Cambodia
The Ministry of Health of Cambodia has announced a new confirmed case of human infection with the H5N1 avian influenza virus. The 19-year-old male, from Kandal Province, developed symptoms on 28 November and initially sought medical attention at a local health centre on 30 November. The presence of the H5N1 virus was confirmed by the National Influenza Centre, the Institut Pasteur in Cambodia, on 11 December. Complete news at...
While radiation treatments deliver precise doses of high-energy X-rays to stop cancer cells from spreading or to shrink tumors, oncologists have become increasingly concerned about inadvertent exposures during head and neck cancer treatments to nerves responsible for upper body mobility. To reduce the possibility of permanent nerve damage, UC Davis Cancer Center researchers have taken the lead in establishing new treatment guidelines for physicians nationwide. Complete news at...
New research claims long-term use of Thiazolidinediones, a class of drugs used to manage Type 2 diabetes, could potentially double some women's risk of breaking a bone. The research by British and American scientists analysed the findings of ten studies involving almost 14,000 people with Type 2 diabetes. The researchers, from the University of East Anglia and Wake Forest University in North Carolina, compared the bone health of those on the drugs with others who were not. Complete news at...
A study in the Dec. 15 issue of the Journal of Clinical Sleep Medicine shows that objectively measured snoring intensity is correlated with subjective sleepiness independent of the apnea-hypopnea index (AHI) in patients with moderate to severe obstructive sleep apnea (OSA). Complete news at...
Type 1 (juvenile) diabetes and celiac disease appear to share a common genetic origin, scientists at the University of Cambridge and Barts and The London School of Medicine and Dentistry, have confirmed. Their findings, which are reported in this week's edition of the New England Journal of Medicine, identified seven chromosome regions which are shared between the two diseases. Complete news at...
The Juvenile Diabetes Research Foundation (JDRF) announced that it has received a $1 million gift focused on accelerating the development of an artificial pancreas from Glen and Trish Tullman. Mr. Tullman is the Chief Executive Officer of Allscripts (Nasdaq: MDRX), a leading provider of electronic health record and electronic prescribing solutions that help physicians, hospitals and patients connect to better healthcare outcomes. Mr. Complete news at...
Interruptions in Medicaid coverage are associated with a higher rate of hospitalization for conditions that can often be treated in an ambulatory care setting, including asthma, diabetes, and hypertension, according to a new study in today's issue of the Annals of Internal Medicine. Complete news at...
More radical measures are needed to tackle childhood obesity, campaigners said this week after figures showed no decline in the number of overweight and obese children. Almost a quarter of four- to five-year-olds in England's primary schools are overweight or obese, according to the latest data from the NHS Information Centre. And almost one in three children aged 10 to 11 are also overweight or obese, the figures showed. Complete news at...
While radiation treatments deliver precise doses of high-energy X-rays to stop cancer cells from spreading or to shrink tumors, oncologists have become increasingly concerned about inadvertent exposures during head and neck cancer treatments to nerves responsible for upper body mobility. To reduce the possibility of permanent nerve damage, UC Davis Cancer Center researchers have taken the lead in establishing new treatment guidelines for physicians nationwide. Complete news at...
New research claims long-term use of Thiazolidinediones, a class of drugs used to manage Type 2 diabetes, could potentially double some women's risk of breaking a bone. The research by British and American scientists analysed the findings of ten studies involving almost 14,000 people with Type 2 diabetes. The researchers, from the University of East Anglia and Wake Forest University in North Carolina, compared the bone health of those on the drugs with others who were not. Complete news at...
A study in the Dec. 15 issue of the Journal of Clinical Sleep Medicine shows that objectively measured snoring intensity is correlated with subjective sleepiness independent of the apnea-hypopnea index (AHI) in patients with moderate to severe obstructive sleep apnea (OSA). Complete news at...
Type 1 (juvenile) diabetes and celiac disease appear to share a common genetic origin, scientists at the University of Cambridge and Barts and The London School of Medicine and Dentistry, have confirmed. Their findings, which are reported in this week's edition of the New England Journal of Medicine, identified seven chromosome regions which are shared between the two diseases. Complete news at...
The Juvenile Diabetes Research Foundation (JDRF) announced that it has received a $1 million gift focused on accelerating the development of an artificial pancreas from Glen and Trish Tullman. Mr. Tullman is the Chief Executive Officer of Allscripts (Nasdaq: MDRX), a leading provider of electronic health record and electronic prescribing solutions that help physicians, hospitals and patients connect to better healthcare outcomes. Mr. Complete news at...
Interruptions in Medicaid coverage are associated with a higher rate of hospitalization for conditions that can often be treated in an ambulatory care setting, including asthma, diabetes, and hypertension, according to a new study in today's issue of the Annals of Internal Medicine. Complete news at...
More radical measures are needed to tackle childhood obesity, campaigners said this week after figures showed no decline in the number of overweight and obese children. Almost a quarter of four- to five-year-olds in England's primary schools are overweight or obese, according to the latest data from the NHS Information Centre. And almost one in three children aged 10 to 11 are also overweight or obese, the figures showed. Complete news at...
Tuesday, December 16, 2008
Mediterranean Low-Clycemic Diet Beneficials For Diabetes
Mediterranean Low-Clycemic Diet Beneficials For Diabetes
Team Solves Failed Vaccine Mystery
Research led by Johns Hopkins Children's Center scientists has figured out why a respiratory syncytial virus vaccine used in 1966 to inoculate children against the infection instead caused severe respiratory disease and effectively stopped efforts to make a better one. The findings, published online on Dec. 14 in Nature Medicine, could restart work on effective killed-virus vaccines not only for RSV but other respiratory viruses, researchers say.
The effectiveness of colonscopy in identifying some colon cancers
TB Case Prompts Screening At University Hospitals Bristol NHS Foundation Trust, England
A healthcare worker from University Hospitals Bristol NHS Foundation Trust, based at the Bristol Royal Infirmary, has been diagnosed with multi-drug resistant Tuberculosis (MDR-TB). All patients who may have had contact with the infected healthcare worker have been identified. As a result of a thorough lookback exercise, 264 patients and staff were yesterday (Monday 8 December) sent a letter offering an appointment for screening as a routine precaution.
More female cardiologists, but still unrepresented
Heart, Stroke Death Rates Down
Persons with type 2 diabetes who had a diet high in low-glycemic foods such as nuts, beans and lentils had greater improvement in glycemic control and risk factors for coronary heart disease than persons on a diet with an emphasis on high-cereal fiber, according to a study in the December 17 issue of JAMA.
One dietary strategy aimed at improving both diabetes control and cardiovascular risk factors is the use of low-glycemic index diets, but there is disagreement over their effectiveness, according to background information in the article.
Team Solves Failed Vaccine Mystery
Research led by Johns Hopkins Children's Center scientists has figured out why a respiratory syncytial virus vaccine used in 1966 to inoculate children against the infection instead caused severe respiratory disease and effectively stopped efforts to make a better one. The findings, published online on Dec. 14 in Nature Medicine, could restart work on effective killed-virus vaccines not only for RSV but other respiratory viruses, researchers say.
The effectiveness of colonscopy in identifying some colon cancers
Physicians should advise patients of colonscopy test limitations in identifying some colon cancers.
Colonoscopy, a key screening test for colon cancer, appears to be less effective in reducing patients’ risk of dying from cancers that originate on the right side of the colon. The groundbreaking research led by St. Michael’s Hospital and the Institute for Clinical and Evaluative Sciences (ICES) was published today on the Annals of Internal Medicine website (www.annals.org) and will be printed in the January 6, 2009 issue.
TB Case Prompts Screening At University Hospitals Bristol NHS Foundation Trust, England
A healthcare worker from University Hospitals Bristol NHS Foundation Trust, based at the Bristol Royal Infirmary, has been diagnosed with multi-drug resistant Tuberculosis (MDR-TB). All patients who may have had contact with the infected healthcare worker have been identified. As a result of a thorough lookback exercise, 264 patients and staff were yesterday (Monday 8 December) sent a letter offering an appointment for screening as a routine precaution.
More female cardiologists, but still unrepresented
Number of female cardiologists nearly doubles, but under-representation and discrimination remain. Ten-year survey reveals progress and challenges amid increasing demand for cardiac care.
The number of female doctors in cardiology nearly doubled in the last decade, and male and female cardiologists both report a high level of job satisfaction, according to findings from a 10-year follow-up survey published in the December 16/23, 2008, issue of the Journal of the American College of Cardiology.
Heart, Stroke Death Rates Down
The age-adjusted death rates for coronary heart disease and stroke have each reached about a 30 percent reduction since 1999, according to the latest data in the American Heart Association’s Heart Disease and Stroke Statistics – 2009 Update, published online in Circulation: Journal of the American Heart Association.
Preventing Metastasis To 'Stop Cancer From Killing People'
Preventing Metastasis To 'Stop Cancer From Killing People'
Metastasis is the ability of cancer cells to spread from a primary site, to form tumours at distant sites. It is a complex process in which cell motility and invasion play a fundamental role. Essential to our understanding of how metastasis develops is identification of the molecules, and characterisation of the mechanisms that regulate cell motility. Hitherto, these mechanisms have been poorly understood.
Clatterbridge Centre For Oncology Ranked As One Of The Best Healthcare Organisations To Work For In The UK
Clatterbridge Centre for Oncology is one of the Top 100 healthcare organisations to work for in the UK according to a survey by the Health Service Journal. The survey asked employees at the Centre a range of questions and the Centre has been included in the Top 100 list! The final results will be announced in March 2009, when the Centre will find out where they came in the top 100.
East Surrey Hospital Reports Cases Of Winter Vomiting Virus, England
Holmwood and Godstone wards have been closed to incoming patients after 18 people at the hospital have developed symptoms of winter vomiting virus. Tests are now being done to find the cause and the wards will remain shut until all symptoms of the bug have cleared. Members of the public are being asked to consider the necessity of their visit to the hospital. No one should visit if they themselves have been unwell within the last week.
Tau Protein Expression Predicts Breast Cancer Survival -- Though Not As Expected
Expression of the microtubule-binding protein Tau is not a reliable means of selecting breast cancer patients for adjuvant paclitaxel chemotherapy, according to research led by The University of Texas M. D. Anderson Cancer Center. Presented Dec. 13, at the CRTC-AACR San Antonio Breast Cancer Symposium, the researchers found that Tau expression does predict survival, yet in an unexpected way. In earlier neoadjuvant studies, investigators from M. D.
Low Income Men Diagnosed More Often With Advanced Prostate Cancer, The Journal Of Urology
Coincident with the widespread adoption of PSA screening, the proportion of American men diagnosed with organ-confined, low risk prostate cancer has increased significantly during the last two decades. In a study scheduled for publication in the February 2009 issue of
Possible Therapeutic Target For Pancreatic Cancer
A possible new therapeutic target for pancreatic cancer, the most lethal form of human cancer, has been identified in the proteins whose DNA recipe comes from gene, "Seven-In-Absentia," according to researchers at the American Society for Cell Biology (ASCB) 48th Annual Meeting, Dec. 13-17, 2008 in San Francisco.
ABRAXANE In Combination With Gemcitabine And Epirubicin Evaluated As Neoadjuvant Treatment For Patients With Locally Advanced Breast Cancer
Abraxis BioScience, Inc. (NASDAQ:ABII), a fully integrated, global biotechnology company, today announced the presentation of preliminary results from a single-arm, open-label, Phase II clinical trial evaluating ABRAXANE® for Injectable Suspension (paclitaxel protein-bound particles for injectable suspension) (albumin- bound) in combination with gemcitabine and epirubicin for the treatment of patients with locally advanced breast cancer (neoadjuvant treatment).
Study Finds That Low-Income Men Are More Likely To Be Diagnosed With Advanced Prostate Cancers
Low-income men are more likely to present with advanced prostate cancers, most likely because they don't receive screening services shown to reduce the diagnosis of later-stage cancers, a UCLA study found. The study focused on a group of disadvantaged men enrolled in the state's IMPACT (Improving Access, Counseling and Treatment for Californians with Prostate Cancer) program, which provides high-quality care to poor, underinsured and uninsured men.
Metastasis is the ability of cancer cells to spread from a primary site, to form tumours at distant sites. It is a complex process in which cell motility and invasion play a fundamental role. Essential to our understanding of how metastasis develops is identification of the molecules, and characterisation of the mechanisms that regulate cell motility. Hitherto, these mechanisms have been poorly understood.
Clatterbridge Centre For Oncology Ranked As One Of The Best Healthcare Organisations To Work For In The UK
Clatterbridge Centre for Oncology is one of the Top 100 healthcare organisations to work for in the UK according to a survey by the Health Service Journal. The survey asked employees at the Centre a range of questions and the Centre has been included in the Top 100 list! The final results will be announced in March 2009, when the Centre will find out where they came in the top 100.
East Surrey Hospital Reports Cases Of Winter Vomiting Virus, England
Holmwood and Godstone wards have been closed to incoming patients after 18 people at the hospital have developed symptoms of winter vomiting virus. Tests are now being done to find the cause and the wards will remain shut until all symptoms of the bug have cleared. Members of the public are being asked to consider the necessity of their visit to the hospital. No one should visit if they themselves have been unwell within the last week.
Tau Protein Expression Predicts Breast Cancer Survival -- Though Not As Expected
Expression of the microtubule-binding protein Tau is not a reliable means of selecting breast cancer patients for adjuvant paclitaxel chemotherapy, according to research led by The University of Texas M. D. Anderson Cancer Center. Presented Dec. 13, at the CRTC-AACR San Antonio Breast Cancer Symposium, the researchers found that Tau expression does predict survival, yet in an unexpected way. In earlier neoadjuvant studies, investigators from M. D.
Low Income Men Diagnosed More Often With Advanced Prostate Cancer, The Journal Of Urology
Coincident with the widespread adoption of PSA screening, the proportion of American men diagnosed with organ-confined, low risk prostate cancer has increased significantly during the last two decades. In a study scheduled for publication in the February 2009 issue of
Possible Therapeutic Target For Pancreatic Cancer
A possible new therapeutic target for pancreatic cancer, the most lethal form of human cancer, has been identified in the proteins whose DNA recipe comes from gene, "Seven-In-Absentia," according to researchers at the American Society for Cell Biology (ASCB) 48th Annual Meeting, Dec. 13-17, 2008 in San Francisco.
ABRAXANE In Combination With Gemcitabine And Epirubicin Evaluated As Neoadjuvant Treatment For Patients With Locally Advanced Breast Cancer
Abraxis BioScience, Inc. (NASDAQ:ABII), a fully integrated, global biotechnology company, today announced the presentation of preliminary results from a single-arm, open-label, Phase II clinical trial evaluating ABRAXANE® for Injectable Suspension (paclitaxel protein-bound particles for injectable suspension) (albumin- bound) in combination with gemcitabine and epirubicin for the treatment of patients with locally advanced breast cancer (neoadjuvant treatment).
Study Finds That Low-Income Men Are More Likely To Be Diagnosed With Advanced Prostate Cancers
Low-income men are more likely to present with advanced prostate cancers, most likely because they don't receive screening services shown to reduce the diagnosis of later-stage cancers, a UCLA study found. The study focused on a group of disadvantaged men enrolled in the state's IMPACT (Improving Access, Counseling and Treatment for Californians with Prostate Cancer) program, which provides high-quality care to poor, underinsured and uninsured men.
Monday, December 15, 2008
Allergists Respond To FDA Committee Recommendation On Asthma Medication, Encourage Patients With Questions To Contact Physicians
The nation's allergists urged a Joint FDA Advisory Committee today to continue to make long-acting beta-2 agonists available for the treatment of moderate-to-severe asthma in appropriate patients. More at...
IDO2 An Active Enzyme To Target In Pancreatic Cancer
An enzyme that is overexpressed in pancreatic cancer cells may hold the key to successfully treating the disease with targeted immunotherapy, researchers from Thomas Jefferson University reported at the 2008 Annual Meeting of the Southern Surgical Association.
Complete news at...A University of Iowa study provides insight into a calcium-sensing enzyme already known to play a role in irregular heartbeats and other critical functions. The researchers showed that the enzyme, calmodulin kinase II (CaM kinase II), contributes to arrhythmia in an extremely rare disease called Timothy syndrome and that inhibiting the enzyme prevents irregular heartbeats.
Complete news at...One in 35 people with colon cancer carry a hereditary form of the disease, according to the second of two studies led by researchers at The Ohio State University Comprehensive Cancer Center.
Based on the finding, researchers recommend screening all colon-cancer patients for Lynch syndrome, the most common inherited form of colon cancer.
Complete news at...A UCLA study shows for the first time how microscopic crystals form sound and gravity sensors inside the inner ear. Located at the ends of cilia — tiny cellular hairs in the ear that move and transmit signals — these crystals play an important role in detecting sound, maintaining balance and regulating movement.
Dislodged ear crystals are to blame for the most common form of vertigo. Known as benign paroxysmal positional vertigo, the disorder plagues up to 10 percent of people older than 60 and causes 20 percent of patients' dizziness complaints.
Complete news at...A University of Iowa researcher and colleagues at the University of Michigan have discovered a direct link between disruption of a critical cellular housekeeping process and fatty liver disease, a condition that causes fat to accumulate in the liver.
Complete news at...A novel angled gantry approach to coronary CT angiography reduced radiation exposure to the breast by more than 50%, according to Thomas Jefferson University researchers.
Ethan Halpern, M.D., associate professor of Radiology at Jefferson Medical College of Thomas Jefferson University in Philadelphia, presented the research at the 94th Scientific Assembly and Annual Meeting of the Radiological Society of North America.
Complete news at...An automated system worked well in helping manage routine chemotherapy side effects in women with metastatic breast cancer, according to research conducted in part at Beaumont Hospital in Royal Oak.
One hundred ninety-four women with an average age of 50 were assessed on 15 symptoms ranging from anxiety to fatigue. Half were randomly assigned to an automated system.
Patients received weekly phone calls for the first four weeks, were called during week six and received a final call during week eight. More than 85 percent of the participants completed the study.
Complete news at...Sunday, December 14, 2008
Food to Avoid With Acid Reflux
When you know that something negatively affects you, it is only wise that you keep away from it and this could not be emphasized in a better way when it comes to the things that we eat. In as much as we want to indulge in the foods we love and feel good about it, it is equally important that we keep in mind that too much of anything is poisonous. Foods that pose a health risk are best avoided if we are to live long.
Saturday, December 13, 2008
Kidney Stones - Useful Treatments For the Sufferers of Kidney Stones
Kidney stones treatment can typically be run with no surgical procedure. Drinking water is the most essential point in assisting to cut growth. Treatment for it is important for a sufferer. Those who have never passed a kidney stone may not realize the seriousness of the symptoms. There is not a lot a person can execute with unbearable pain other than seek emergency care. If this is the initial incident and no prior diagnosis has been established, it is significant to be observed by a physician.
Potential For Early Cancer Diagnosis Technique
A team led by a Northwestern University biomedical engineer has developed a new optical technique that holds promise for minimally invasive screening methods for the early diagnosis of cancer. The researchers have shown for the first time that nanoscale changes are present in cells extremely early on in carcinogenesis. Continue reading ...
The International Agency for Research on Cancer (IARC), a division of the World Health Organization (WHO), has released updated cancer death projections in a call to action, asking the government to help fund cancer prevention and research initiatives and international tobacco control policies. According to the report, the burden of cancer doubled globally between 1975 and 2000, and cancer is expected to become the leading cause of death worldwide in 2010. Continue reading ...
"Young men undergoing treatment for cancer often want to know how the disease and its treatment affect their chances of fathering healthy children. Our large-scale study shows that there is a slightly higher risk of deformities, but the actual risk of having a child with deformities is nevertheless extremely low. I think this is good news!" These words are from the cancer physician Olof Stahl, who has studied this issue in his coming dissertation from Lund University in Sweden. Continue reading ...
Dr. De Yang, Senior Scientist of the Cellular Immunology Group at the National Cancer Institute of the National Institutes of Health will present at the 7th Cytokines and Inflammation Conference on January 29-30, 2009 in San Diego, CA. Dr. Yang from the NCI will give a presentation on "Alarmin Regulation of Inflammation and Immunity" on January 30, 2009 at 8:45 on the second morning of the conference. Dr. Continue reading ...
SAN ANTONIO - Investigators are reporting favorable early results using RAD001 (Afinitor) combined with weekly paclitaxel and trastuzumab to treat patients with HER-2 overexpressing metastatic breast cancer who have demonstrated prior resistance to trastuzumab. The results, released here at the 2008 San Antonio Breast Cancer Symposium (SABCS), show that RAD001 combined with trastuzumab and chemotherapy halted tumor growth in 77 percent of patients. Continue reading ...
Michael Karin, Professor of Pharmacology Tumor Growth Invasion and Metastasis at UCSD to Give Keynote Speech at GTCbio's 7th Cytokines and Inflammation Conference on January 29-30, 2009 in San Diego, CA Dr. Continue reading ...
The International Agency for Research on Cancer (IARC), a division of the World Health Organization (WHO), has released updated cancer death projections in a call to action, asking the government to help fund cancer prevention and research initiatives and international tobacco control policies. According to the report, the burden of cancer doubled globally between 1975 and 2000, and cancer is expected to become the leading cause of death worldwide in 2010. Continue reading ...
"Young men undergoing treatment for cancer often want to know how the disease and its treatment affect their chances of fathering healthy children. Our large-scale study shows that there is a slightly higher risk of deformities, but the actual risk of having a child with deformities is nevertheless extremely low. I think this is good news!" These words are from the cancer physician Olof Stahl, who has studied this issue in his coming dissertation from Lund University in Sweden. Continue reading ...
Dr. De Yang, Senior Scientist of the Cellular Immunology Group at the National Cancer Institute of the National Institutes of Health will present at the 7th Cytokines and Inflammation Conference on January 29-30, 2009 in San Diego, CA. Dr. Yang from the NCI will give a presentation on "Alarmin Regulation of Inflammation and Immunity" on January 30, 2009 at 8:45 on the second morning of the conference. Dr. Continue reading ...
SAN ANTONIO - Investigators are reporting favorable early results using RAD001 (Afinitor) combined with weekly paclitaxel and trastuzumab to treat patients with HER-2 overexpressing metastatic breast cancer who have demonstrated prior resistance to trastuzumab. The results, released here at the 2008 San Antonio Breast Cancer Symposium (SABCS), show that RAD001 combined with trastuzumab and chemotherapy halted tumor growth in 77 percent of patients. Continue reading ...
Michael Karin, Professor of Pharmacology Tumor Growth Invasion and Metastasis at UCSD to Give Keynote Speech at GTCbio's 7th Cytokines and Inflammation Conference on January 29-30, 2009 in San Diego, CA Dr. Continue reading ...
Friday, December 12, 2008
Breast Cancer - AstraZeneca's Response To Letrozole Datapresented At San Antonio Breast Cancer Symposium (SABCS), 11 -14 December 2008
AstraZeneca is pleased to see additional data presented at SABCS reinforce that there is no evidence that a sequencing strategy is superior to a 5 year aromatase inhibitor (AIs) strategy. AstraZeneca believes that AIs should be used upfront in all newly diagnosed breast cancer postmenopausal women as it is critical to keep patients cancer free for as long as possible. Complete news at...
Dr. Samir Hanash, Program Head at the Fred Hutchinson Cancer Research Center in Seattle, WA will give the keynote address on the discovery and development of biomarkers at the 2nd annual Oncology Biomarkers Conference on January 19-20, 2009 in Miami, Florida. Dr. Complete news at...
Intercell AG (VSE: ICLL) announced the execution of a contract modification with the U.S. Department of Health and Human Services (HHS). The agreement commits additional funding of USD 12.5 m for Intercell's Pandemic Influenza program. Intercell is developing a Pandemic Influenza Vaccine Patch System that includes an immunostimulant patch administered in conjunction with an injected Pandemic Influenza vaccine (manufactured by Solvay Biologicals, B.V. Complete news at...
In a new tactic in the fight against cancer, Cornell University researcher Michael King has developed what he calls a lethal "lint brush" for the blood -- a tiny, implantable device that captures and kills cancer cells in the bloodstream before they spread through the body. Complete news at...
Vical Incorporated (Nasdaq: VICL) announced that the company's Vaxfectin(R)-formulated H5N1 pandemic influenza DNA vaccines induced T-cell responses against a matching strain of influenza virus and demonstrated cross-clade antibody responses against a different strain in a Phase 1 clinical trial. The company previously reported that the vaccines had achieved potentially protective levels of antibody responses in up to 67% of evaluable subjects in the trial's higher dose cohorts. Complete news at...
Douglas Easton, Ph.D., whose international studies in breast cancer explained the genetic patterns and causes of the BRCA1 and BRCA2 gene mutations which indicate a person's risk for breast cancer, has been selected to receive the inaugural American Association for Cancer Research (AACR) Outstanding Investigator Award in Breast Cancer Research. This award, funded by Susan G. Complete news at...
Dr. Samir Hanash, Program Head at the Fred Hutchinson Cancer Research Center in Seattle, WA will give the keynote address on the discovery and development of biomarkers at the 2nd annual Oncology Biomarkers Conference on January 19-20, 2009 in Miami, Florida. Dr. Complete news at...
Intercell AG (VSE: ICLL) announced the execution of a contract modification with the U.S. Department of Health and Human Services (HHS). The agreement commits additional funding of USD 12.5 m for Intercell's Pandemic Influenza program. Intercell is developing a Pandemic Influenza Vaccine Patch System that includes an immunostimulant patch administered in conjunction with an injected Pandemic Influenza vaccine (manufactured by Solvay Biologicals, B.V. Complete news at...
In a new tactic in the fight against cancer, Cornell University researcher Michael King has developed what he calls a lethal "lint brush" for the blood -- a tiny, implantable device that captures and kills cancer cells in the bloodstream before they spread through the body. Complete news at...
Vical Incorporated (Nasdaq: VICL) announced that the company's Vaxfectin(R)-formulated H5N1 pandemic influenza DNA vaccines induced T-cell responses against a matching strain of influenza virus and demonstrated cross-clade antibody responses against a different strain in a Phase 1 clinical trial. The company previously reported that the vaccines had achieved potentially protective levels of antibody responses in up to 67% of evaluable subjects in the trial's higher dose cohorts. Complete news at...
Douglas Easton, Ph.D., whose international studies in breast cancer explained the genetic patterns and causes of the BRCA1 and BRCA2 gene mutations which indicate a person's risk for breast cancer, has been selected to receive the inaugural American Association for Cancer Research (AACR) Outstanding Investigator Award in Breast Cancer Research. This award, funded by Susan G. Complete news at...
The Truth About Using Drugs to Cure Osteoporosis
If nothing is done, bone problems could get worse and turn into agonizing and unbearable bone problems causing confinement or worse. This essay looks for answers to some key questions concerning the use of drugs in treating bone problems. People experience a reduction in mineral density in their bones, as a result either because of the normal wear of age, or as a result of lack of calcium. In its more advanced stage, this decline in bone density is described as Osteoporosis, where the bones become porous and fracture easily.
Are Physicians Overusing An Invasive Cardiac Treatment?
Researchers are asking if cardiology patients receive intervention-type treatments, such as stents, too often and too quickly.
In regions of the country where cardiologists perform high numbers of cardiac catheterizations to diagnose heart problems, patients may be receiving a treatment known as percutaneous cardiac intervention (PCI) more than they need or want, according to a study published online this week in the journal Circulation. The study will also be in the journal's December 16/23 print edition.
More at...New data released today demonstrate that the addition of Zometa (zoledronic acid) injection to standard chemotherapy before breast cancer surgery reduces the size of breast tumors more effectively than chemotherapy alone in women with early-stage disease.
More at...The American Academy of Orthopaedic Surgeons (AAOS) has approved and released an evidence-based clinical practice guideline on "Treatment of Osteoarthritis of the Knee". These guidelines were explicitly developed to include only treatments which are less invasive than knee replacement surgery. While a wide range of treatment options are available, they should always be tailored to individual patients after discussions with their physicians.
The Guidelines and Evidence Report recommends:
More at...Thursday, December 11, 2008
New Way Of Viewing Cells Could Lead To Easier Routes For Drug Manufacture
Research by a Michigan State University chemist could eventually lead to a quicker and easier way of developing protein-based drugs that are key to treating a number of diseases, including cancer, diabetes and hepatitis. Proteins used in drug manufacture and research often are made within genetically modified Escherichia coli, a one-cell bacteria. That protein tends to collect into what scientists call inclusion bodies. More at...
Alnylam Pharmaceuticals, Inc. (Nasdaq: ALNY), a leading RNAi therapeutics company, announced today that it has formed an exclusive collaboration with the University of California, San Francisco (UCSF) to evaluate the potential of an RNAi therapeutic targeting a heterotrimeric G protein alpha-subunit, known as G-alpha q or GNAQ, for the treatment of metastatic uveal melanoma. More at...
Guided Therapeutics, Inc. (GT) (Pink Sheets: GTHP) today announced it submitted the first of three modules of its Premarket Approval (PMA) application to the U.S. Food and Drug Administration (FDA) for the LightTouchTM non-invasive cervical cancer detection device. More at...
Abraxis BioScience, Inc. (NASDAQ:ABII), a fully integrated, global biotechnology company, today announced that multiple studies of ABRAXANE® for Injectable Suspension (paclitaxel protein-bound particles for injectable suspension) (albumin bound) will be presented at the 31st Annual San Antonio Breast Cancer Symposium on December 10-14, 2008. More at...
Alnylam Pharmaceuticals, Inc. (Nasdaq: ALNY), a leading RNAi therapeutics company, announced today that it has formed an exclusive collaboration with the University of California, San Francisco (UCSF) to evaluate the potential of an RNAi therapeutic targeting a heterotrimeric G protein alpha-subunit, known as G-alpha q or GNAQ, for the treatment of metastatic uveal melanoma. More at...
Guided Therapeutics, Inc. (GT) (Pink Sheets: GTHP) today announced it submitted the first of three modules of its Premarket Approval (PMA) application to the U.S. Food and Drug Administration (FDA) for the LightTouchTM non-invasive cervical cancer detection device. More at...
Abraxis BioScience, Inc. (NASDAQ:ABII), a fully integrated, global biotechnology company, today announced that multiple studies of ABRAXANE® for Injectable Suspension (paclitaxel protein-bound particles for injectable suspension) (albumin bound) will be presented at the 31st Annual San Antonio Breast Cancer Symposium on December 10-14, 2008. More at...
The Key to Avoidance
It seems like avoidance is one of the first keys to not getting sick and not getting a deadly disease. If you avoid people with the flu then your chances of getting it are far less than if you are around those who are in the infectious stage. The same goes for a cold and for lots of other obvious diseases and infections but what about the really big ones? What do you avoid to not get cancer? There are just too many things in our environment labeled as a carcinogen.
Hospitals' Cost For The Top 6 Cardiovascular Treatments Nearing $60 Billion, USA
Hospitals' Cost For The Top 6 Cardiovascular Treatments Nearing $60 Billion, USA
Treating heart attack victims, opening clogged arteries and treating other common cardiovascular conditions cost U.S. hospitals $57.9 billion in 2006 - about 40 percent more than in 1997, according to the latest News and Numbers from the Agency for Healthcare Research and Quality. Most of this growth in costs, however, occurred between 1997 and 2003.
Panic Attacks Linked To Higher Risk Of Heart Attacks And Heart Disease, Especially In Younger People
People who have been diagnosed with panic attacks or panic disorder have a greater risk of subsequently developing heart disease or suffering a heart attack than the normal population, with higher rates occurring in younger people, according to research published in Europe's leading cardiology journal, the European Heart Journal [1] today (Thursday 11 December).
Treating heart attack victims, opening clogged arteries and treating other common cardiovascular conditions cost U.S. hospitals $57.9 billion in 2006 - about 40 percent more than in 1997, according to the latest News and Numbers from the Agency for Healthcare Research and Quality. Most of this growth in costs, however, occurred between 1997 and 2003.
Panic Attacks Linked To Higher Risk Of Heart Attacks And Heart Disease, Especially In Younger People
People who have been diagnosed with panic attacks or panic disorder have a greater risk of subsequently developing heart disease or suffering a heart attack than the normal population, with higher rates occurring in younger people, according to research published in Europe's leading cardiology journal, the European Heart Journal [1] today (Thursday 11 December).
Wednesday, December 10, 2008
Cholinesterase Inhibitors Reduce Aggression, Wandering And Paranoia In Alzheimer's Disease
Cholinesterase inhibitors, used to treat cognitive symptoms of Alzheimer's disease, are also a safe and effective alternative therapy for the behavioral and psychological symptoms of dementia, according to a study that appears in the December 2008 edition of Clinical Interventions in Aging. Complete news at...
Sciele Pharma, Inc., a Shionogi Company, and Plethora Solutions Holdings PLC ("Plethora" - AIM:PLE), the specialist developer of products for the treatment and management of urological disorders, today announced the final analysis of its European Phase III double-blind placebo-controlled study of PSD502 for the treatment of premature ejaculation ('PE'). Complete news at...
Sciele Pharma, Inc., a Shionogi Company, and Plethora Solutions Holdings PLC ("Plethora" - AIM:PLE), the specialist developer of products for the treatment and management of urological disorders, today announced the final analysis of its European Phase III double-blind placebo-controlled study of PSD502 for the treatment of premature ejaculation ('PE'). Complete news at...
Celiac - Intolerance to Gluten
The celiaquia or intolerance to gluten is a condition that is manifested mainly by a rather complex immunological disorder afflicting the small intestine caused directly by the same element (gluten) but it is good to ask what is gluten? Gluten is an element that is found in foods like oats, barley and wheat, and more on whether the type of food grain, this element in the feeding of a person tolerant to it is quite useful in regulating some systems as the digestive and absorcivo but for people with celiac or intolerant, this element is highly damaging ...
Health Problems Aggravate Cholera Outbreak In Zimbabwe
Health Problems Aggravate Cholera Outbreak In Zimbabwe
San Diego Addresses Obesity, Diabetes Among American Indians
Surge in older cancer survivors expected as baby boomers age
CDC Releases Data On HIV Transmission Rates In US
Namibia Launches HIV/AIDS Booster Packs For Teachers
Genetic Test For Adolescent Idiopathic Scoliosis Launched
Overweight Siblings Of Diabetes Children With Usually Have Abnormal Blood Sugar Levels
A widespread cholera outbreak, under-resourced and under-staffed health system, and inadequate access to safe drinking water and hygiene are threatening the wellbeing of thousands of Zimbabweans. As of 9 December, 16 141 suspected cases of cholera and 775 resultant deaths (case fatality rate of 4.8%) had been recorded since August in two-thirds of the country's 62 districts.
San Diego Addresses Obesity, Diabetes Among American Indians
Health care professionals and educators in the San Diego area held a conference last week to focus on obesity and diabetes among American Indians, particularly children, the San Diego Union-Tribune reports.
In San Diego County, nearly one-third of American Indians ages five to 19 were obese in 2004, compared with 25% of the general population, according to the Union-Tribune. Diabetes, particularly type 2, is linked to obesity.
Surge in older cancer survivors expected as baby boomers age
Oncologists, geriatricians, primary care providers increasingly challenged to provide timely and appropriate post-treatment care to older cancer survivors.
The United States could be faced with a national health care crisis in the coming decades as the country's baby boomer population ages and a growing number of older adults find themselves diagnosed with and living longer with cancer.
CDC Releases Data On HIV Transmission Rates In US
CDC in a research letter published in the Journal of Acquired Immune Deficiency Syndromes released updated estimates of HIV transmission rates in the U.S., Reuters reports. According to the letter -- written by researchers from CDC and Johns Hopkins University -- the HIV transmission rate in the U.S. has decreased by 89% since 1984 and 33% since 1997.
Namibia Launches HIV/AIDS Booster Packs For Teachers
Namibia's Ministry of Education has made immune system booster packs part of its efforts to mitigate the effects of HIV/AIDS on the education sector in the country, the Namibian/AllAfrica.com reports. The packs aim to ensure that teachers and other education ministry employees who are living with HIV have strong immune systems, enabling antiretroviral therapy to be more effective.
Genetic Test For Adolescent Idiopathic Scoliosis Launched
Axial Biotech, Inc. announced today the commercial launch of a new DNA-based test that indicates the likelihood of progression to a severe curve for children diagnosed with Adolescent Idiopathic Scoliosis (AIS).
This new molecular diagnostic tool marks a major advancement in which medical treatments can be personalized to patients diagnosed with this deforming disease. The test will be marketed under the name of ScoliScore AIS Prognostic Test.
Overweight Siblings Of Diabetes Children With Usually Have Abnormal Blood Sugar Levels
Overweight siblings of children with type 2 diabetes are four times more likely to have abnormal glucose levels compared to other overweight children. Because abnormal glucose levels may indicate risk for diabetes or diabetes itself, these children could benefit from screening tests and diabetes prevention education.
Researchers from The Children's Hospital of Philadelphia published their findings today in the online edition of the Journal of Pediatrics.
Tuesday, December 9, 2008
Plagued With Cancer
Our world seems to be plagued with cancer, and some of those cancers are a direct result of our polluting the environment. We surrounded our selves with chemicals of many combination's, from herbicides to pesticides and fertilizers. Then we eat our nutritionally depleted food that we grow in the same soil every year. Foods that are chalk full of chemicals that have weak bonds between there molecules. These food products then cause oxidization in the cells of our bodies, setting the stage for cancer and other disease.
Malaria Vaccine Effective in Latest Trials
Malaria Vaccine Effective in Latest Trials
Title: Malaria Vaccine Effective in Latest Trials
Category: Health News
Created: 12/9/2008 2:00:00 AM
Last Editorial Review: 12/9/2008
Rib-X Pharmaceuticals Reports Positive Top-Line Results From Phase 2 Study Of Delafloxacin
Rib-X Pharmaceuticals, Inc. ("Rib-X" or the "Company"), a development-stage company focused on the discovery, development and commercialization of novel antibiotics for the treatment of antibiotic-resistant infections, announced positive topline results from a Phase 2 clinical trial with the intravenous form of its novel anionic quinolone antibiotic, delafloxacin (RX-3341).
A Signaling Protease Required For Melanization In Drosophila Affects Resistance And Tolerance Of Infections
Organisms evolve two routes to surviving infections-they can resist pathogen growth (resistance) and they can endure the pathogenesis of infection (tolerance). The sum of these two properties together defines the defensive capabilities of the host. Typically, studies of animal defenses focus on either understanding resistance or, to a lesser extent, tolerance mechanisms, thus providing little understanding of the relationship between these two mechanisms.
Discovery Of Microbe In Roundworm Provides Animal Model For 'Emerging Pathogen'
Microsporidia are single-celled parasites that are capable of causing infections in humans - primarily people with compromised immune systems, such as those infected with HIV or who have undergone organ transplants. An article in this week's issue of PLoS Biology documents a newly discovered species of microsporidia, which infects C. elegans, the round worm used as a model system by developmental biologists.
Novavax Announces Preclinical Data For Respiratory Syncytial Virus Vaccine Candidate
Novavax, Inc. (Nasdaq: NVAX) announced that Dr. Trudy Morrison, PhD, Professor of Molecular Genetics and Microbiology, University of Massachusetts Medical School, will be presenting the results of a preclinical study of a vaccine candidate for the prevention of respiratory syncytial virus ("RSV") at the 2nd Vaccine Congress in Boston, MA on December 9, 2008. This study was funded by Novavax, Inc.
New Mexico, Texas, Colorado Alerts Bus Passengers To TB Case That Traveled In August
The New Mexico, Colorado, and Texas Departments of Health announced today that a person recently diagnosed with infectious tuberculosis (TB) in New Mexico traveled on an interstate commercial bus that originated from El Paso, Texas. The bus traveled through New Mexico to its final destination of Greeley, Colorado.
Title: Malaria Vaccine Effective in Latest Trials
Category: Health News
Created: 12/9/2008 2:00:00 AM
Last Editorial Review: 12/9/2008
Rib-X Pharmaceuticals Reports Positive Top-Line Results From Phase 2 Study Of Delafloxacin
Rib-X Pharmaceuticals, Inc. ("Rib-X" or the "Company"), a development-stage company focused on the discovery, development and commercialization of novel antibiotics for the treatment of antibiotic-resistant infections, announced positive topline results from a Phase 2 clinical trial with the intravenous form of its novel anionic quinolone antibiotic, delafloxacin (RX-3341).
A Signaling Protease Required For Melanization In Drosophila Affects Resistance And Tolerance Of Infections
Organisms evolve two routes to surviving infections-they can resist pathogen growth (resistance) and they can endure the pathogenesis of infection (tolerance). The sum of these two properties together defines the defensive capabilities of the host. Typically, studies of animal defenses focus on either understanding resistance or, to a lesser extent, tolerance mechanisms, thus providing little understanding of the relationship between these two mechanisms.
Discovery Of Microbe In Roundworm Provides Animal Model For 'Emerging Pathogen'
Microsporidia are single-celled parasites that are capable of causing infections in humans - primarily people with compromised immune systems, such as those infected with HIV or who have undergone organ transplants. An article in this week's issue of PLoS Biology documents a newly discovered species of microsporidia, which infects C. elegans, the round worm used as a model system by developmental biologists.
Novavax Announces Preclinical Data For Respiratory Syncytial Virus Vaccine Candidate
Novavax, Inc. (Nasdaq: NVAX) announced that Dr. Trudy Morrison, PhD, Professor of Molecular Genetics and Microbiology, University of Massachusetts Medical School, will be presenting the results of a preclinical study of a vaccine candidate for the prevention of respiratory syncytial virus ("RSV") at the 2nd Vaccine Congress in Boston, MA on December 9, 2008. This study was funded by Novavax, Inc.
New Mexico, Texas, Colorado Alerts Bus Passengers To TB Case That Traveled In August
The New Mexico, Colorado, and Texas Departments of Health announced today that a person recently diagnosed with infectious tuberculosis (TB) in New Mexico traveled on an interstate commercial bus that originated from El Paso, Texas. The bus traveled through New Mexico to its final destination of Greeley, Colorado.
Monday, December 8, 2008
Are Americans Just Too Chronically Ill?
Are Americans simply too healthy to be sick than any other people in other countries in the world, or they simply have more access to a better health care system? If they are just too healthy, then why are there so many health insurance companies in the US, perhaps some of the largest health insurance companies than any other health insurance companies in the world? Or if the American people are just as sick as other people in the world, then do they just have access to a better healthcare system? What class of American people is sicker then the other; men or women, young or old?
Podcasts: HIV Transmission Rates in the United States
Podcasts: HIV Transmission Rates in the United States
This podcast describes in detail HIV transmission rates in the United States and the success of prevention efforts nationwide.
HIV Transmission Rates in the United States
This fact sheet examines a journal article from JAIDS which shows that HIV transmission has declined significantly since the early days of the epidemic and indicates success in HIV prevention efforts.
This podcast describes in detail HIV transmission rates in the United States and the success of prevention efforts nationwide.
HIV Transmission Rates in the United States
This fact sheet examines a journal article from JAIDS which shows that HIV transmission has declined significantly since the early days of the epidemic and indicates success in HIV prevention efforts.
Sunday, December 7, 2008
Acid Reflux - Foods to Avoid
Acid reflux disease or Gastro Esophageal Reflux Disease (GERD) is a disease that happens when stomach contents pass through the overrelaxed lower esophageal sphincter and irritate the esophageal lining. This kind of disease, which left untreated, can lead to some forms of cancer. So, since acid reflux is like other diseases which can be triggered by eating certain foods, what are the safe foods for acid reflux and which should be avoided? What are the food you should not eat if you have acid reflux? Find out.
Saturday, December 6, 2008
Maintaining The Brain's Wiring In Ageing And Disease
Maintaining The Brain's Wiring In Ageing And Disease
Researchers at the Babraham Institute near Cambridge, supported by the Alzheimer's Research Trust and the Biotechnology and Biological Sciences Research Council (BBSRC), have discovered that the brain's circuitry survives longer than previously thought in diseases of ageing such as Alzheimer's disease. The findings were published in the journal Brain. Alzheimer's disease causes nerve cells in the brain to die, resulting in problems with memory, speech and understanding.
Sufferers Of Dementia Benefit From Mix Of Taiji, Cognitive Therapy And Support Groups
Those diagnosed with early stage dementia can slow their physical, mental and psychological decline by taking part in therapeutic programs that combine counseling, support groups, Taiji and qigong, researchers report. Some of the benefits of this approach are comparable to those achieved with anti-dementia medications. The findings are detailed in the American Journal of Alzheimer's Disease and Other Dementias.
Researchers at the Babraham Institute near Cambridge, supported by the Alzheimer's Research Trust and the Biotechnology and Biological Sciences Research Council (BBSRC), have discovered that the brain's circuitry survives longer than previously thought in diseases of ageing such as Alzheimer's disease. The findings were published in the journal Brain. Alzheimer's disease causes nerve cells in the brain to die, resulting in problems with memory, speech and understanding.
Sufferers Of Dementia Benefit From Mix Of Taiji, Cognitive Therapy And Support Groups
Those diagnosed with early stage dementia can slow their physical, mental and psychological decline by taking part in therapeutic programs that combine counseling, support groups, Taiji and qigong, researchers report. Some of the benefits of this approach are comparable to those achieved with anti-dementia medications. The findings are detailed in the American Journal of Alzheimer's Disease and Other Dementias.
Some Home Remedies For Acid Reflux
It is only natural for us to go looking for professional assistance when face with health problems, but giving a thought to some simple procedures that we can do on our own at home to deal with some ailments could go a long way in saving us a lot of money, that which we use to pay medical bills and to buy medicines. When faced with continuous ad persistent acid reflux, you may want to visit your doctor, but wait a minute. Have you tried some of the home remedies for acid reflux?
Wyeth Submits European Marketing Authorization Application For Its 13-Valent Vaccine For The Prevention Of Pneumococcal Disease
Wyeth Pharmaceuticals, a division of Wyeth (NYSE:WYE), announced that it has submitted a marketing authorization application (MAA) to the European Medicines Agency (EMEA) for approval to market its investigational 13-valent pneumococcal conjugate vaccine (PCV13) for infants and young children. Read more ...
RHEI Pharmaceuticals, Inc. announced that the final clinical trial for Tibozole, a locally active antifungal with low dose miconazole in a patented mucoadhesive system, has been initiated in China. This will be the last clinical trial conducted for submission of the New Drug Application (NDA) to the State Food and Drug Administration (SFDA) in China. RHEI licensed Tibozole from Tibotec, a Johnson and Johnson company. Read more ...
ASM Press announces publication of the latest volume in its popular series on new and emerging infectious diseases. Based on sessions at recent scientific conferences, Emerging Infections 8 offers up-to-date information and the most current research on new and emerging infections that have generated international interest. Read more ...
RHEI Pharmaceuticals, Inc. announced that the final clinical trial for Tibozole, a locally active antifungal with low dose miconazole in a patented mucoadhesive system, has been initiated in China. This will be the last clinical trial conducted for submission of the New Drug Application (NDA) to the State Food and Drug Administration (SFDA) in China. RHEI licensed Tibozole from Tibotec, a Johnson and Johnson company. Read more ...
Newly formed consortium to advance eradication of inflammatory breast cancer.
The University of Texas M. D. Anderson Cancer Center will hold the first international inflammatory breast cancer (IBC) conference on December 6-7, to bring together internationally recognized breast cancer clinicians and scientists.
Participants will present new clinical discoveries and participate in educational workshops, with the goal of improving diagnosis and management of this rare but deadly disease.
Read more ...ASM Press announces publication of the latest volume in its popular series on new and emerging infectious diseases. Based on sessions at recent scientific conferences, Emerging Infections 8 offers up-to-date information and the most current research on new and emerging infections that have generated international interest. Read more ...
Friday, December 5, 2008
Cancer Research Giants Collaborate To Present The CTRC-AACR San Antonio Breast Cancer Symposium
Cancer Research Giants Collaborate To Present The CTRC-AACR San Antonio Breast Cancer Symposium
This year marks the first San Antonio Breast Cancer Symposium to include the collaborative efforts of the American Association for Cancer Research, the Cancer Therapy and Research Center at the University of Texas Health Science Center at San Antonio and the Baylor College of Medicine.
More Than 200 Abstracts At ASH And SABCS Reveal Potential Compelling Patient Benefits From Novartis Oncology Current And Pipeline Therapies
More than 200 abstracts from therapies across the Novartis Oncology portfolio will be presented at two December medical congresses, providing new data and profiling potential patient benefits from ongoing collaboration with the oncology community.
Gene Packaging Tells Story Of Cancer Development
To decipher how cancer develops, Johns Hopkins Kimmel Cancer Center investigators say researchers must take a closer look at the packaging. Specifically, their findings in the December 2, 2008, issue of PLoS Biology point to the three dimensional chromatin packaging around genes formed by tight, rosette-like loops of Polycomb group proteins (PcG).
Geron Announces Initiation Of Phase I Clinical Trial Of Vaccine Candidate Targeting Telomerase By Merck & Co., Inc.
Geron Corporation (Nasdaq:GERN) announced today that its collaborator, Merck & Co., Inc., has initiated a Phase I clinical trial of V934/V935, a non-dendritic cell based cancer vaccine candidate targeting telomerase. The trial will assess the safety, tolerability and immunogenicity of the vaccine candidate in patients with solid tumors, including non-small cell lung cancer and prostate carcinoma.
VentiRx Pharmaceuticals Commences Phase I Clinical Trial Of VTX-2337, A Novel TLR8 Agonist For The Treatment Of Oncology
VentiRx Pharmaceuticals, Inc., a biopharmaceutical company focused on the development of novel Toll-Like Receptor 8 (TLR8) agonists for the treatment of cancer, respiratory and autoimmune diseases, announced today that it has initiated a Phase I clinical trial of VTX-2337, a selective TLR8 agonist for the treatment of cancer. The multi-center clinical trial is being conducted at the Mayo Clinic Arizona and TGen Drug Development Services (TD2) both in Scottsdale, Arizona.
This year marks the first San Antonio Breast Cancer Symposium to include the collaborative efforts of the American Association for Cancer Research, the Cancer Therapy and Research Center at the University of Texas Health Science Center at San Antonio and the Baylor College of Medicine.
More Than 200 Abstracts At ASH And SABCS Reveal Potential Compelling Patient Benefits From Novartis Oncology Current And Pipeline Therapies
More than 200 abstracts from therapies across the Novartis Oncology portfolio will be presented at two December medical congresses, providing new data and profiling potential patient benefits from ongoing collaboration with the oncology community.
Gene Packaging Tells Story Of Cancer Development
To decipher how cancer develops, Johns Hopkins Kimmel Cancer Center investigators say researchers must take a closer look at the packaging. Specifically, their findings in the December 2, 2008, issue of PLoS Biology point to the three dimensional chromatin packaging around genes formed by tight, rosette-like loops of Polycomb group proteins (PcG).
Geron Announces Initiation Of Phase I Clinical Trial Of Vaccine Candidate Targeting Telomerase By Merck & Co., Inc.
Geron Corporation (Nasdaq:GERN) announced today that its collaborator, Merck & Co., Inc., has initiated a Phase I clinical trial of V934/V935, a non-dendritic cell based cancer vaccine candidate targeting telomerase. The trial will assess the safety, tolerability and immunogenicity of the vaccine candidate in patients with solid tumors, including non-small cell lung cancer and prostate carcinoma.
VentiRx Pharmaceuticals Commences Phase I Clinical Trial Of VTX-2337, A Novel TLR8 Agonist For The Treatment Of Oncology
VentiRx Pharmaceuticals, Inc., a biopharmaceutical company focused on the development of novel Toll-Like Receptor 8 (TLR8) agonists for the treatment of cancer, respiratory and autoimmune diseases, announced today that it has initiated a Phase I clinical trial of VTX-2337, a selective TLR8 agonist for the treatment of cancer. The multi-center clinical trial is being conducted at the Mayo Clinic Arizona and TGen Drug Development Services (TD2) both in Scottsdale, Arizona.
Acid Reflux Symptoms and Signs
Acid reflux is a condition that can be quite frustrating and irritating because it produces a burning sensation and at the wrong time, that is just when you are about to start enjoying your good night's sleep. It would therefore be of help to you if you got an idea of what the acid reflux symptoms are like so that you are able to take precautions well in advance before you are rudely jolted out of bed to look for antacids. Among the most common characteristics of this condition is frequency of heartburn.
Late-Onset Hypogonadism: New Recommendations By Scientific Societies
Late-Onset Hypogonadism: New Recommendations By Scientific Societies
The January issue of European Urology, the official journal of the European Association of Urology published by Elsevier, will feature new recommendations on late-onset hypogonadism (LOH), recently formulated by major scientific organizations. LOH is a clinical and biochemical syndrome associated with advancing age and characterized by typical symptoms and a deficiency in serum testosterone levels.
The January issue of European Urology, the official journal of the European Association of Urology published by Elsevier, will feature new recommendations on late-onset hypogonadism (LOH), recently formulated by major scientific organizations. LOH is a clinical and biochemical syndrome associated with advancing age and characterized by typical symptoms and a deficiency in serum testosterone levels.
Thursday, December 4, 2008
What's the Harm?
In addition to preventing toxins from being sweat out of the body, antiperspirants contain Aluminum Chlorohydrate, as an active ingredient. The suspicion of aluminum as one of the contributing factors to Alzheimer's started back in the 1950's. In more recent years it has also been related Breast Cancer. One of the ways that women may increase their risk is by the application of an antiperspirant right after shaving because shaving causes very tiny nicks in the skin that allow these chemicals an easy entrance into the body.
Landmark EchoCRT Trial Enrolls First European Patients
Landmark EchoCRT Trial Enrolls First European Patients
BIOTRONIK announced that the first European patients have been enrolled into the EchoCRT (Echocardiography guided Cardiac Resynchronization Therapy) trial by the team of physicians at Hospital ClÃnic in Barcelona, Spain, led by Professor Dr. Josep Brugada, Director of the Thorax Institute, Chairman of the Cardiology Department, EchoCRT Executive Committee Member and President of the European Heart Rhythm Association.
CT-Scan Vs. Invasive Angiography: Statement From The ESC
Recent media reports based on a new study published in the New England Journal of Medicine (27 November 2008 issue) have announced that "noninvasive CT scans cannot replace imaging of coronary artery blockages by conventional invasive angiography". In response, imaging specialist Professor Juhani Knuuti, spokesperson for the European Society of Cardiology and Past-Chair of the ESC Working Group on Nuclear Cardiology and Cardiac CT, emphasizes the following points.
Medtronic Launches Sprinter(R) Angioplasty Balloon Cathethers On Rapid Exchange
Expanding its angioplasty product portfolio, Medtronic, Inc. (NYSE: MDT), announced today the U.S. market launch of the Sprinter Legend (semicompliant) and the NC Sprinter (noncompliant) balloon dilatation catheters on a rapid exchange delivery system. Recently approved by the U.S.
Two Drug Blood Pressure Therapy Reduces Heart Attacks
While doctors are urged to start with a diuretic-based strategy to control patients' high blood pressure, an international blood pressure study shows a different single-pill drug combination is more effective at preventing heart-related events such as heart attacks and strokes. The findings challenge the way blood pressure is usually treated worldwide. The randomized study led by a University of Michigan Health System researcher compared two drug combinations.
Multi-Translated HeartScore Revises Its Approach To Risk Assessment In Young Patients
A new release of HeartScore® the interactive tool designed to predict and help manage the risk of heart attack and stroke in Europe created by the European Society of Cardiology (ESC) was launched on Tuesday 18 November 2008 at http://www.HeartScore.org. This revised version includes relative risk for younger patients, in addition to patient data history and progress monitoring.
Investigating Numbness, Pain Or Muscle Weakness? Guidelines Identify Best Tests For Neuropathy
New guidelines developed by the American Academy of Neurology find a combination of blood tests and other specialized assessments appear to be the most helpful tests for finding the cause of neuropathy. Also known as neuritis or distal symmetric polyneuropathy, this common nerve problem affects people of all ages. The guidelines are published in the December 3, 2008, online issue of Neurology®, the medical journal of the American Academy of Neurology.
ConjuChem's PC-DAC(TM):Exendin-4 Lowers Glucose And Weight In Phase II Diabetes Trials
ConjuChem Biotechnologies, Inc. (TSX:CJB) announced preliminary results today showing that its Type 2 diabetes product, PC-DAC(TM):Exendin-4, achieved statistically significant reductions in HbA1c and weight in its two Phase II clinical trials. Commenting on the clinical results, Mark Perrin, President and CEO stated, "We are extremely pleased with these results which have met our clinical objectives. Achieving a 1.
Deborah Heart & Lung Center Receives Top Honors For Outstanding Cardiovascular Outcomes
The highest designation given to hospitals by the Society of Thoracic Surgeons (STS), a three-star rating for quality of heart surgery, has been awarded to Deborah Heart and Lung Center in Browns Mills, N.J. Only ten percent of heart centers throughout the nation attain this level. "We are extremely proud of our entire cardiac team for demonstrating the hard work and dedication that warrants a three-star rating," said Lynn B. McGrath, M.D.
BIOTRONIK announced that the first European patients have been enrolled into the EchoCRT (Echocardiography guided Cardiac Resynchronization Therapy) trial by the team of physicians at Hospital ClÃnic in Barcelona, Spain, led by Professor Dr. Josep Brugada, Director of the Thorax Institute, Chairman of the Cardiology Department, EchoCRT Executive Committee Member and President of the European Heart Rhythm Association.
CT-Scan Vs. Invasive Angiography: Statement From The ESC
Recent media reports based on a new study published in the New England Journal of Medicine (27 November 2008 issue) have announced that "noninvasive CT scans cannot replace imaging of coronary artery blockages by conventional invasive angiography". In response, imaging specialist Professor Juhani Knuuti, spokesperson for the European Society of Cardiology and Past-Chair of the ESC Working Group on Nuclear Cardiology and Cardiac CT, emphasizes the following points.
Medtronic Launches Sprinter(R) Angioplasty Balloon Cathethers On Rapid Exchange
Expanding its angioplasty product portfolio, Medtronic, Inc. (NYSE: MDT), announced today the U.S. market launch of the Sprinter Legend (semicompliant) and the NC Sprinter (noncompliant) balloon dilatation catheters on a rapid exchange delivery system. Recently approved by the U.S.
Two Drug Blood Pressure Therapy Reduces Heart Attacks
While doctors are urged to start with a diuretic-based strategy to control patients' high blood pressure, an international blood pressure study shows a different single-pill drug combination is more effective at preventing heart-related events such as heart attacks and strokes. The findings challenge the way blood pressure is usually treated worldwide. The randomized study led by a University of Michigan Health System researcher compared two drug combinations.
Multi-Translated HeartScore Revises Its Approach To Risk Assessment In Young Patients
A new release of HeartScore® the interactive tool designed to predict and help manage the risk of heart attack and stroke in Europe created by the European Society of Cardiology (ESC) was launched on Tuesday 18 November 2008 at http://www.HeartScore.org. This revised version includes relative risk for younger patients, in addition to patient data history and progress monitoring.
Investigating Numbness, Pain Or Muscle Weakness? Guidelines Identify Best Tests For Neuropathy
New guidelines developed by the American Academy of Neurology find a combination of blood tests and other specialized assessments appear to be the most helpful tests for finding the cause of neuropathy. Also known as neuritis or distal symmetric polyneuropathy, this common nerve problem affects people of all ages. The guidelines are published in the December 3, 2008, online issue of Neurology®, the medical journal of the American Academy of Neurology.
ConjuChem's PC-DAC(TM):Exendin-4 Lowers Glucose And Weight In Phase II Diabetes Trials
ConjuChem Biotechnologies, Inc. (TSX:CJB) announced preliminary results today showing that its Type 2 diabetes product, PC-DAC(TM):Exendin-4, achieved statistically significant reductions in HbA1c and weight in its two Phase II clinical trials. Commenting on the clinical results, Mark Perrin, President and CEO stated, "We are extremely pleased with these results which have met our clinical objectives. Achieving a 1.
Deborah Heart & Lung Center Receives Top Honors For Outstanding Cardiovascular Outcomes
The highest designation given to hospitals by the Society of Thoracic Surgeons (STS), a three-star rating for quality of heart surgery, has been awarded to Deborah Heart and Lung Center in Browns Mills, N.J. Only ten percent of heart centers throughout the nation attain this level. "We are extremely proud of our entire cardiac team for demonstrating the hard work and dedication that warrants a three-star rating," said Lynn B. McGrath, M.D.
Wednesday, December 3, 2008
Women's Health - 5 Things You Can Do to Prevent Cancer
Cancer is something that a lot of people worry about getting. If cancer is found at an early stage, then it can be taken care of. However, cancer can spread around the body, and thus, the best way to get rid of cancer is to not get it. Today we are going to talk about the five things that you should do that can help you avoid getting cancer all together. These things can help keep you safe and help keep you healthy for a long time to come.
Adult Survivors Of Childhood Cancer Have Lower Bone Mineral Density
Adult Survivors Of Childhood Cancer Have Lower Bone Mineral Density
Cancer Mortality Rate Declines Are Promising
Secreted Protein Sends Signal That Fat Is On The Way
After you eat a burger and fries or other fat-filled meal, a protein produced by the liver may send a signal that fat is on the way, suggests a report in the December issue of the journal Cell Metabolism, a Cell Press publication. Researchers have found in mice that the liver produces a protein called adropin, which rises in response to high-fat foods and falls after fasting.
Ten Percent Of Children Sleep In School
Absence Of Frank Talk About HIV/AIDS Hurts Black Women
New tool helps target bone treatment
Researchers Reveal What Makes The Heart 'Tick-Tock'
Researchers have new evidence to show that the heart beats to its own drummer, according to a report in the December issue of the journal Cell Metabolism, a Cell Press publication. They've uncovered some of the molecular circuitry within the cardiovascular system itself that controls the daily rise and fall of blood pressure and heart rate. The findings might also explain why commonly used diabetes drugs come with cardiovascular benefits, according to the researchers.
Examining Male Circumcision For HIV Prevention
Men who survived childhood leukemia treatment into adulthood were more likely to have low bone mineral density than other adults their age, putting them at risk of osteoporosis and bone fractures, according to a new study.
Cancer Mortality Rate Declines Are Promising
The latest annual report on cancer trends shows "that a long-term decline in death rates has continued for both sexes," and there "seems little doubt that the decline in cancer death rates since the early 1990s is real," a New York Times editorial states.
"If the decline means that fewer people are contracting cancer, then that is great news," the editorial continues, adding, "But if it simply means that fewer cases are being diagnosed because fewer people are getting screened for breast and prostate cancer or can afford to visit a doctor, then that is bad news."
Secreted Protein Sends Signal That Fat Is On The Way
After you eat a burger and fries or other fat-filled meal, a protein produced by the liver may send a signal that fat is on the way, suggests a report in the December issue of the journal Cell Metabolism, a Cell Press publication. Researchers have found in mice that the liver produces a protein called adropin, which rises in response to high-fat foods and falls after fasting.
Ten Percent Of Children Sleep In School
Up to 10% of children starting school suffer from sleep disturbances and these may lead to poor performance or behavioral difficulties. In the current edition of Deutsches Ärzteblatt International (Dtsch Arztebl Int 2007; 105[47]: 809-14), the child and adolescent psychiatrist Gerd Lehmkuhl and his colleagues present the results of a study from Cologne, Germany.
Absence Of Frank Talk About HIV/AIDS Hurts Black Women
"If ever there was a case for unvarnished sex education in public schools, the ongoing AIDS epidemic in black America ought to be it," columnist Courtland Milloy writes in a Washington Post opinion piece, adding, "[H]ow can we teach [HIV prevention] if we can't talk frankly?"
New tool helps target bone treatment
New method will help doctors better identify patients at high risk of bone fracture.
Better targeted, more cost-effective osteoporosis treatment could soon be a reality worldwide. A new method (1) for determining more accurately at which point someone needs further diagnostic tests, or when immediate treatment is warranted, has been developed by The National Osteoporosis Guideline Group in the UK.
Researchers Reveal What Makes The Heart 'Tick-Tock'
Researchers have new evidence to show that the heart beats to its own drummer, according to a report in the December issue of the journal Cell Metabolism, a Cell Press publication. They've uncovered some of the molecular circuitry within the cardiovascular system itself that controls the daily rise and fall of blood pressure and heart rate. The findings might also explain why commonly used diabetes drugs come with cardiovascular benefits, according to the researchers.
Examining Male Circumcision For HIV Prevention
The Los Angeles Times and the Journal of the American Medical Association recently published opinion pieces about male circumcision as a method of HIV prevention. Summaries appear below.
Tuesday, December 2, 2008
Candidiasis Treatment - Natural and Conventional Methods
Candida albicans/yeast infections are quite common and can be treated. Candidiasis is a kind of parasitic yeastlike fungus that lives in the intestines, mouth, esophagus, genital tract, and throat. As a rule, our bodies maintain a healthy balance of bacteria, but sometimes certain situations can lead to an overgrowth of the bad bacteria (candida). When candida overrides the good bacteria, it depresses the immune system and moves through the bloodstream to many areas of the body. The good news is that there are many candidiasis treatments available; alternative as well as conventional approaches.
Wistar Scientists Find Key To Keeping Killer T Cells In Prime Shape For Fighting Infection, Cancer
Wistar Scientists Find Key To Keeping Killer T Cells In Prime Shape For Fighting Infection, Cancer
Like tuning a violin to produce strong, elegant notes, researchers at The Wistar Institute have found multiple receptors on the outside of the body's killer immune system cells which they believe can be selectively targeted to keep the cells in superb infection- and disease-fighting condition.
Harnessing MiRNA Natural Gene Repressors For Anticancer Therapy
Michel Sadelain and colleagues, at Memorial Sloan-Kettering Cancer Center, New York, have developed a new approach to modulate the expression of genes for therapeutic purposes, and used this to mediate effective anticancer therapy in mice. Small, noncoding RNA molecules known as miRNAs are powerful natural repressors of gene expression.
Genaera Begins Phase 1b Trial Of Trodusquemine (MSI-1436) In Overweight And Obese Type 2 Diabetics
Genaera Corporation (Nasdaq: GENR) announced that dosing of subjects has begun in study MSI-1436C-102 (Study 102), the multiple ascending dose Phase 1b study of trodusquemine (MSI-1436) in overweight and obese type 2 diabetics. MSI-1436 is a novel therapeutic for the treatment of type 2 diabetes and obesity which works centrally and peripherally to regulate insulin and leptin pathways through the highly selective inhibition of its novel target enzyme, PTP-1B.
Study Demonstrates The Benefit Of Using Chemoradiotherapy In Elderly Patients With Locally Advanced Oesophageal Cancer
Chemoradiotherapy (CRT) can be considered an "effective" treatment for elderly patients with locally advanced oesophageal cancer, reports the British Journal of Cancer. The French study, involving 109 consecutive patients with oesophageal cancer, suggests that characterising patients first with the "Charlson" score may provide useful criteria for deciding which subjects are suitable for treatment.
Nationwide Study Confirms PET As The Most Powerful Imaging Tool In Cancer Management
With the most recent release of data from the National Oncologic PET Registry (NOPR), researchers may have reached the moment of critical mass by confirming the effectiveness of positron emission tomography (PET) in the monitoring of tumor activity across a wide range of cancers.
Like tuning a violin to produce strong, elegant notes, researchers at The Wistar Institute have found multiple receptors on the outside of the body's killer immune system cells which they believe can be selectively targeted to keep the cells in superb infection- and disease-fighting condition.
Harnessing MiRNA Natural Gene Repressors For Anticancer Therapy
Michel Sadelain and colleagues, at Memorial Sloan-Kettering Cancer Center, New York, have developed a new approach to modulate the expression of genes for therapeutic purposes, and used this to mediate effective anticancer therapy in mice. Small, noncoding RNA molecules known as miRNAs are powerful natural repressors of gene expression.
Genaera Begins Phase 1b Trial Of Trodusquemine (MSI-1436) In Overweight And Obese Type 2 Diabetics
Genaera Corporation (Nasdaq: GENR) announced that dosing of subjects has begun in study MSI-1436C-102 (Study 102), the multiple ascending dose Phase 1b study of trodusquemine (MSI-1436) in overweight and obese type 2 diabetics. MSI-1436 is a novel therapeutic for the treatment of type 2 diabetes and obesity which works centrally and peripherally to regulate insulin and leptin pathways through the highly selective inhibition of its novel target enzyme, PTP-1B.
Study Demonstrates The Benefit Of Using Chemoradiotherapy In Elderly Patients With Locally Advanced Oesophageal Cancer
Chemoradiotherapy (CRT) can be considered an "effective" treatment for elderly patients with locally advanced oesophageal cancer, reports the British Journal of Cancer. The French study, involving 109 consecutive patients with oesophageal cancer, suggests that characterising patients first with the "Charlson" score may provide useful criteria for deciding which subjects are suitable for treatment.
Nationwide Study Confirms PET As The Most Powerful Imaging Tool In Cancer Management
With the most recent release of data from the National Oncologic PET Registry (NOPR), researchers may have reached the moment of critical mass by confirming the effectiveness of positron emission tomography (PET) in the monitoring of tumor activity across a wide range of cancers.
The Quest To Cure Disfiguring Parasitic Disease May Lead To Targeted, Less Toxic Treatment For Dreaded Leishmania Parasite
The Quest To Cure Disfiguring Parasitic Disease May Lead To Targeted, Less Toxic Treatment For Dreaded Leishmania Parasite
Eating a meal in a restaurant is one of those trivial, everyday activities we take for granted in the developed world. For Canadian aid worker Louisette Pouliot, however, the simple act of grabbing a quick bite at an outdoor eatery in Ouagadougou, the capital of the African nation of Burkina Faso, had profound implications for her life and health. "I was in Ouagadougou in the fall of 2006 and ate outdoors at restaurants without having any insecticide with me," she recalled.
Eating a meal in a restaurant is one of those trivial, everyday activities we take for granted in the developed world. For Canadian aid worker Louisette Pouliot, however, the simple act of grabbing a quick bite at an outdoor eatery in Ouagadougou, the capital of the African nation of Burkina Faso, had profound implications for her life and health. "I was in Ouagadougou in the fall of 2006 and ate outdoors at restaurants without having any insecticide with me," she recalled.
Monday, December 1, 2008
6 Illnesses Contracted From an Unhygienic Office
Our offices are vulnerable to disease and illness purely because of the diverse nature of the people who work in them. You and I may make a concerted effort to keep our area of the office clean but how many others are even cognisant of the dangers lurking in the communal coffee mugs and other shared items? The vast majority of us do not have the time to take our meal and coffee breaks properly and instead we chow down in front of the computer but how many of us bother to clean up afterwards?
Parents Of New Babies Should Be Considered For A Whooping Cough Booster, Say Experts
A booster vaccination for parents of new babies and other household members may be the most effective way of preventing the fatal form of whooping cough in young infants, say a group of paediatric intensive care doctors on http://www.bmj.com today. Whooping cough (pertussis) is a distressing infectious disease which affects infants and young children. Read more ...
As part of its investigation into a rare infection that can be associated with infant formula, the New Mexico Department of Health is advising people on the safest way to prepare formula. The Department of Health is investigating two cases of Enterobacter sakazakii illness, a rare cause of bloodstream and central nervous system infections, in a female infant from Lea County and a male infant from Otero County. The male infant has died, and the female infant is hospitalized. Read more ...
It appears that human ganulocytic anaplasmosis (HGA) has been identified in China for the first time, and was transmitted between two humans rather than ticks, according to a study published on November 19, 2008 in JAMA. HGA, usually carried by ticks, and has symptoms similar to those of influenza. HGA has been noted in the United States since 1990 and Europe since 1997. Read more ...
Following a Request for Proposal issued in 2007 with the intent to procure an MVA-based, third generation smallpox vaccine, Public Works and Government Services Canada, on behalf of the Canadian Department of National Defence, has awarded a contract to Bavarian Nordic for the delivery of IMVAMUNE®. The Canadian authorities intend to use IMVAMUNE® as part of the country's bio-preparedness programme. Read more ...
Hospitals in Lincolnshire are taking a pro-active approach to battling infections by screening patients for MRSA on admission. At the moment, the United Lincolnshire Hospitals NHS Trust screens patients for MRSA who are admitted as an emergency and other groups dependant upon the types of procedures to be undertaken. Now the trust is working towards screening all elective patients for the infection, on admission, by March 2009. Read more ...
Although naturally occurring smallpox was eradicated in 1977, there is concern that bioterrorists might obtain smallpox from a laboratory and release it into the population. Under such circumstances, the supply of smallpox vaccine may be insufficient for universal administration. Read more ...
An international team of biochemists has discovered how an experimental drug unleashes its destructive force inside the bacteria that cause tuberculosis (TB). The finding could help scientists develop ways to treat dormant TB infections, and suggests a strategy for drug development against other bacteria as well. A report describing the research, led by Clifton E. Barry, III, Ph.D. Read more ...
As part of its investigation into a rare infection that can be associated with infant formula, the New Mexico Department of Health is advising people on the safest way to prepare formula. The Department of Health is investigating two cases of Enterobacter sakazakii illness, a rare cause of bloodstream and central nervous system infections, in a female infant from Lea County and a male infant from Otero County. The male infant has died, and the female infant is hospitalized. Read more ...
It appears that human ganulocytic anaplasmosis (HGA) has been identified in China for the first time, and was transmitted between two humans rather than ticks, according to a study published on November 19, 2008 in JAMA. HGA, usually carried by ticks, and has symptoms similar to those of influenza. HGA has been noted in the United States since 1990 and Europe since 1997. Read more ...
Following a Request for Proposal issued in 2007 with the intent to procure an MVA-based, third generation smallpox vaccine, Public Works and Government Services Canada, on behalf of the Canadian Department of National Defence, has awarded a contract to Bavarian Nordic for the delivery of IMVAMUNE®. The Canadian authorities intend to use IMVAMUNE® as part of the country's bio-preparedness programme. Read more ...
Hospitals in Lincolnshire are taking a pro-active approach to battling infections by screening patients for MRSA on admission. At the moment, the United Lincolnshire Hospitals NHS Trust screens patients for MRSA who are admitted as an emergency and other groups dependant upon the types of procedures to be undertaken. Now the trust is working towards screening all elective patients for the infection, on admission, by March 2009. Read more ...
Although naturally occurring smallpox was eradicated in 1977, there is concern that bioterrorists might obtain smallpox from a laboratory and release it into the population. Under such circumstances, the supply of smallpox vaccine may be insufficient for universal administration. Read more ...
An international team of biochemists has discovered how an experimental drug unleashes its destructive force inside the bacteria that cause tuberculosis (TB). The finding could help scientists develop ways to treat dormant TB infections, and suggests a strategy for drug development against other bacteria as well. A report describing the research, led by Clifton E. Barry, III, Ph.D. Read more ...
Plumbagin, A Medicinal Plant-Derived Naphthoquinone, Is A Novel Inhibitor Of The Growth And Invasion Of Hormone-Refractory Prostate Cancer
UroToday.com - Dr. Moammir Aziz and colleagues from the University of Wisconsin reported in the November 1, 2008 issue of Cancer Research that plumbagin, a medicinal plant derived naphthoquinone, inhibits castration-resistant prostate cancer (CaP) growth and invasion. Plumbagin was isolated from the roots of plumbago zeylannica L. (Chitrak), which has been used in Indian medicine for thousands of years. Read more ...
UroToday.com - Accurate molecular markers for targeted therapy that correlate with traditional clinical outcomes are not common. An online article from a distinguished group of researchers demonstrates how useful this approach may be. As background, the combination of platelet-derived growth factor receptor (PDGFR) inhibition and taxane chemotherapy for CaP patients with bone metastasis has not demonstrated improved progression-free survival or overall survival benefit. Read more ...
Diabetes and endocrinology specialists at Leighton Hospital in Crewe and Victoria Infirmary, Northwich, can access a summary of the patient's primary care record, enabling them to make more informed decisions at the point of care and helping them to advise a greater number of patients. Read more ...
UroToday.com - Accurate molecular markers for targeted therapy that correlate with traditional clinical outcomes are not common. An online article from a distinguished group of researchers demonstrates how useful this approach may be. As background, the combination of platelet-derived growth factor receptor (PDGFR) inhibition and taxane chemotherapy for CaP patients with bone metastasis has not demonstrated improved progression-free survival or overall survival benefit. Read more ...
Diabetes and endocrinology specialists at Leighton Hospital in Crewe and Victoria Infirmary, Northwich, can access a summary of the patient's primary care record, enabling them to make more informed decisions at the point of care and helping them to advise a greater number of patients. Read more ...
Subscribe to:
Posts (Atom)
