Saturday, January 31, 2009

Urologist, J. Francois Eid, M.D., Lauds Improvements In Penile Prosthesis And Artificial Urinary Sphincter Technologies

Urologist, J. Francois Eid, M.D., Lauds Improvements In Penile Prosthesis And Artificial Urinary Sphincter Technologies
Dr. J. Francois Eid has performed more internal penile implant surgeries than anyone in the world and has built a reputation for excellence in the treatment of erectile dysfunction (ED).

HIV Testing Implementation Guidance for Correctional Settings

HIV Testing Implementation Guidance for Correctional Settings
This document provides background statistics on HIV/AIDS in correctional facilities and covers issues relating to inmate privacy and confidentiality, opt-out HIV screening in correctional medical clinics, HIV testing procedures, and HIV/AIDS case reporting.

Friday, January 30, 2009

Global Antibiotic Resistance Initiative launched by Resources For The Future

Global Antibiotic Resistance Initiative launched by Resources For The Future
Resources for the Future have launched a new global health initiative to explore incentives to slow the development and spread of resistance to lifesaving antibiotics by promoting their prudent use in developing nations. The Global Antibiotic Resistance Partnership was established with the support of a grant of more than $2 million from the Bill & Melinda Gates Foundation.

Thursday, January 29, 2009

Alzheimer's Society Statement On Help The Aged Research Into Ageism In The NHS

Research undertaken by the British Geriatrics Society on behalf of Help the Aged has revealed that 47% of doctors specialising in the care of older people think the NHS is institutionally ageist. 77% of doctors would support the introduction of legislation against age discrimination in the NHS. The research also revealed that 66% agreed that, in their experience, older people are less likely to have symptoms fully investigated. Read more ...

Gastric Cancer: Magnetic-Anchor-Guided Endoscopic Submucosal Dissection Shows Promise

A prospective clinical trial from researchers in Japan shows magnetic-anchor-guided endoscopic submucosal dissection for large early gastric cancer to be a feasible and safe method in humans. Endoscopic submucosal dissection (ESD) is useful in the en bloc removal (in a single large piece) of large gastric lesions because it reduces the risk of a local recurrence caused by removing the lesions piecemeal (in multiple small pieces). Read more ...

Wednesday, January 28, 2009

Study Uncovers Long-Sought Mechanism That Limits Centriole Duplication, With Implications For Potential Cancer Treatments

Study Uncovers Long-Sought Mechanism That Limits Centriole Duplication, With Implications For Potential Cancer Treatments
Like DNA, centrioles need to duplicate only once per cell cycle. Rogers et al. uncover a long-sought mechanism that limits centriole copying, showing that it depends on the timely demolition of a protein that spurs the organelles' replication. The study appears in the January 26, 2009 issue of the Journal of Cell Biology and online at http://www.jcb.org.

Tuesday, January 27, 2009

ICardiac's COMPAS Technology Validated In Peer Reviewed Publication Co-Authored By FDA And University Of Rochester

ICardiac's COMPAS Technology Validated In Peer Reviewed Publication Co-Authored By FDA And University Of Rochester
iCardiac Technologies, Inc., a leader in advanced cardiac safety biomarker development, today announced that Computers in Cardiology has published an article by authors from the University of Rochester and the FDA demonstrating the use of the Highly Automated QT technology in data analysis in Thorough QT studies.

Effects Of Urinary Tract Infection In Patients With Bladder Augmentation And Kidney Transplantation

Effects Of Urinary Tract Infection In Patients With Bladder Augmentation And Kidney Transplantation
UroToday.com - A study from Brazil evaluated kidney transplantation in relation to urinary tract infection and bladder augmentation. This study showed 23 children who had undergone bladder augmentation and then had renal transplantation were retrospectively compared to 42 controls matched for gender, age, race, donor type, weight, and immunosuppression protocol in regards to graft outcome.

Monday, January 26, 2009

Obama Cancer Plan Should Prioritize Prevention

President Barack Obama is the first new President to develop a comprehensive cancer plan.

While the plan reflects strong emphasis on oncology, disturbingly no reference is made to prevention, and the wide range of avoidable causes of cancer.

read more

More at...

Saturday, January 24, 2009

Treating Brain Hemorrhage Early Improves Outcomes

Treating Brain Hemorrhage Early Improves Outcomes

Treating brain bleeding quickly, and at hospitals that handle many brain attack emergencies can help ensure the best outcomes for patients, according to updated guidelines published today in Stroke: Journal of the American Heart Association.

read more


Friday, January 23, 2009

How lungs fight bacteria and prevent infection

How lungs fight bacteria and prevent infection

Did you know that many patients die from lung complications of a disease, rather than the disease itself. Actor and pancreatic cancer patient Patrick Swayze's recent hospitalization with pneumonia as a result of his compromised immune system underscores the sensitivity of the lungs.

Almost like an open wound lungs are delicate and exposed to the environment. Consequently, the body has developed an elaborate immuno-defense system to combat inhaled pathogens and bacteria – in a healthy individual, this system effectively blocks hundreds of potentially sickening assaults daily.

read more


Thursday, January 22, 2009

Alzheimer's Drug Discovery Foundation Funds Development Of Clinical Tests For Alzheimer's Disease

Alzheimer's Drug Discovery Foundation Funds Development Of Clinical Tests For Alzheimer's Disease
The Alzheimer's Drug Discovery Foundation (ADDF) awarded the British firm of Cambridge Cognition Ltd. a grant of $200,000 to assist in their development of a clinical cognitive assessment product for Alzheimer's disease.

Comparing Two Non- Pharmacological GERD (Gastroesophageal Reflux Disease) Treatments

Comparing Two Non- Pharmacological GERD (Gastroesophageal Reflux Disease) Treatments
According to an article published in Archives of Surgery, two non-pharmacological GERD (gastroesophageal reflux disease) treatments seem to be effective in lowering medication use and improving swallowing symptoms as well as the patient's voice. One of the assessed therapies appears to be effective in reducing heartburn and cough. The other one reduces regurgitation. Archives of Surgery is a JAMA/Archives journal.

Wednesday, January 21, 2009

Comparing Two Non- Pharmacological GERD (Gastroesophageal Reflux Disease) Treatments

According to an article published in Archives of Surgery, two non-pharmacological GERD (gastroesophageal reflux disease) treatments seem to be effective in lowering medication use and improving swallowing symptoms as well as the patient's voice. One of the assessed therapies appears to be effective in reducing heartburn and cough. The other one reduces regurgitation. Archives of Surgery is a JAMA/Archives journal. More at...

Commissioner Jerry Farrell, Jr. announced that genetic testing on the 5-lb unopened tub of King Nut peanut butter found by food inspectors last week at a West Haven distributor has produced the first independently confirmed genetic match for the salmonella strain responsible for the nationwide outbreak. This finding definitively links the peanut butter sample implicated in the recent outbreak back to the manufacturer, Peanut Corporation of America. More at...

Nationwide Medical/Surgical has recently announced they will carry the Flu Vaccine for the 2009-2010 flu season. They will carry flu vaccines made by several manufacturers in several different formats including 10-dose vials and pre-filled syringes. The 2007-2008 flu season was allegedly the worst year of the last four for adult deaths by flu and pneumonia. More at...

Clif Bar & Company announced a voluntary recall of CLIF® and LUNA® branded bars that contain peanut butter because the products have the potential to be contaminated with Salmonella. The recalled products contain peanut butter manufactured by Peanut Corporation of America (PCA). PCA is the focus of an investigation by the U.S. Food and Drug Administration (FDA) concerning a recent Salmonella outbreak thought to be caused by tainted peanut butter. More at...

In terms of diversity and sheer numbers, the microbes occupying the human gut easily dwarf the billions of people inhabiting the Earth. Numbering in the tens of trillions and representing many thousands of distinct genetic families, this microbiome, as it's called, helps the body perform a variety of regulatory and digestive functions, many still poorly understood. More at...

New research supports a modest beneficial effect of anakinra for rheumatoid arthritis patients, but warns against potential risks for serious infections and its use with other biologic medications. Rheumatoid arthritis is a chronic inflammatory disease affecting as many as one in 100 people worldwide. It affects the joints, making them stiff and painful. Anakinra is one of a new breed of arthritis drugs licensed in the past decade called 'biologics'. More at...

Arkansas has joined the growing list of states affected by an ongoing outbreak of Salmonella Typhimurium that began in early September. Four Arkansas residents have tested positive for the same Salmonella strain. The cases are spread across the state with no apparent connection that can be determined. More at...

Dr. Mark Horton, director of the California Department of Public Health (CDPH), today warned consumers not to handle or consume frozen Peanut Butter Cookie Dough distributed by Sweet Success Fundraising Inc, of Ontario, California because of potential contamination with Salmonella. The Department further recommends that any dough that has been thawed or baked should also be discarded. More at...

Tuesday, January 20, 2009

New Criteria For Measuring Tumour Size And Progression Will Help Ease Workloads In Clinical Trials

The first, formal revision of specific guidelines, known as RECIST, used by clinicians to measure tumour size and response to treatment, has been published today (Tuesday 20 January) in a special issue of the European Journal of Cancer (the official journal of ECCO - the European CanCer Organisation) [1]. Complete news at...

PREVIEW: Please join us for lunch and a preview on 27 January 2009, 1 - 2.30pm, Breast Cancer Haven, Effie Road, London, SW6 1TB Speakers: Caroline Hoffman, Clinical Director, Breast Cancer Haven. Dr Andrew Vallance-Owen, Bupa's Group Medical Director. Professor Dudley Sinnett, Consultant Breast Surgeon. Complete news at...

Decision Resources, one of the world's leading research and advisory firms for pharmaceutical and healthcare issues, finds that a drug for treating stage IV malignant melanoma that can increase median overall survival when compared with standard of care dacarbazine (Bedford Laboratories' DTIC-Dome, generics) would earn a higher patient share in the U.S. (60 percent) than in Europe (40 percent), according to surveyed U.S. and European oncologists. Complete news at...

Dr Sarah Cant, Policy Manager at Breakthrough Breast Cancer, says: "This research, whilst interesting, is only relevant to a very small proportion of women - those with a strong family history but without a BRCA gene fault. The researchers suggest that these women could benefit from extra breast screening and taking tamoxifen to reduce their breast cancer risk. However, tamoxifen is not currently licensed for this use in the UK. Complete news at...

Researchers long ago established a link between inflammation, cancer and the compound nitric oxide, which may be produced when the immune system responds to bacterial infections, including those of the colon. However, the exact nature of the relationship was unknown - until now. Complete news at...

Researchers at Mayo Clinic have found that the experimental drug they are testing to treat a deadly form of thyroid cancer turns on a powerful tumor suppressor capable of halting cell growth. Few other cancer drugs have this property, they say. In the Feb. 15 issue of Cancer Research (available online Jan. 20), they report that RS5444, being tested in a Phase 1/2 clinical trial to treat anaplastic thyroid cancer, might be useful for treating other cancers. Complete news at...

A chemical commonly used in the manufacture of rubber products may cause cancer in workers regularly exposed to it, suggests research published ahead of print in Occupational and Environmental Medicine. The researchers base their findings on higher than expected rates of certain cancers, and deaths from the disease, among men working at a rubber chemicals plant in North Wales. Complete news at...

Monday, January 19, 2009

Two Thirds Of Doctors Against Moving Antibiotic Trimethoprim To OTC

Two Thirds Of Doctors Against Moving Antibiotic Trimethoprim To OTC
Almost two thirds of doctors are opposed to the Medicines and Healthcare products Regulatory Agency (MHRA) plans to make the antibiotic trimethoprim available over the counter, according to a survey of readers of an influential journal.

Research!America Selects Ambassador To Join Distinguished Health Experts In Seeking Greater US Investment In Global Health
Research!America honored Dr. Keith C. Norris, the executive vice president for Research and Health Affairs at Charles Drew University of Medicine and Science, by naming him an "ambassador" for the nonprofit organization's Paul G. Rogers Society for Global Health Research. The Rogers Society, named for the late Florida Congressman Paul G. Rogers (1921-2008), a champion for health research and Research!America chair emeritus, advocates for greater U.S.

King's Winning Fight Against Clostridium Difficile
Figures published today by the Health Protection Agency (HPA) show that King's College Hospital has seen a major reduction in the number of cases of Clostridium difficile reported at the Trust. During the most recent quarter for which figures are available (July to September 2008), there were 35 cases of Clostridium difficile recorded at King's. This is a major reduction on the number of cases reported between April and June 2008, which was 99.

Cobalis Corp Gets Federal Court Approval To Launch Its Flagship Anti-Allergy Product PreHistin™
Cobalis Corp. (OTC:CLSC), a pharmaceutical biotech Company specializing in the development of anti-allergy medications, announced the planned marketing launch of the flagship anti-allergy product PreHistin™ after approval in Federal Court in Santa Ana, CA on Jan. 13, 2009. The launch of PreHistin™ is scheduled for February 2009, and will enable the company to be discharged from Chapter 11. Cobalis Corp.

For Cold And Flu Season, The Wrong Prescription Is Free Antibiotics
With an epidemic of antibiotic-resistant infections growing, experts are warning grocery-store pharmacies that antibiotics giveaways are an unhealthy promotional gimmick. If grocery stores want to help customers and save them money during cold and flu season, the Infectious Diseases Society of America (IDSA) says, they should offer free influenza vaccinations instead. Giant, Stop & Shop, and other grocery stores have recently begun offering free antibiotics at their pharmacies.

ViraCor Laboratories Launches Fastest Available Cytomegalovirus Antiviral Resistance Test
ViraCor Laboratories, the leader in molecular diagnostic testing for infectious diseases, announced the launch of a new cytomegalovirus (CMV) antiviral resistance test that provides diagnosis days faster than other tests on the market. Developed in ViraCor's laboratories, the molecular test accurately detects key genetic mutations associated with antiviral resistance in CMV in three days or less. Turnaround time on most CMV antiviral resistance tests is up to two weeks.

Cardioprotective Effects Beyond Blood Pressure Reduction Provided By Salt Reduction

A study published in the February 2009 issue of the American Journal of Clinical Nutrition shows that salt reduction may offer cardioprotective effects beyond blood pressure reduction. The study was led by Kacie Dickinson of Flinders University, South Australia. "Reducing your salt intake provides more benefit than a decrease in blood pressure," said ASN Spokesperson Mary Ann Johnson, PhD. Continue reading ...

Challenging heart rhythm disorders, or arrhythmias, require electrophysiology (EP) technologies to pinpoint and ultimately fix problem areas within the heart's electrical circuitry during an interventional procedure. As EP procedure volume increases worldwide, clinicians are requesting intuitive, advanced tools to help shorten procedure times and gain detailed visualizations for interventions. Continue reading ...

Saturday, January 17, 2009

Few Canadians Aware Of Peripheral Arterial Disease Clogged Arteries In The Legs

Few Canadians Aware Of Peripheral Arterial Disease Clogged Arteries In The Legs
Two out of three Canadians are not aware of peripheral arterial disease (P.A.D.), a common vascular disease that affects as many as 800,000 Canadians, according to a study published in the Canadian Journal of Cardiology. Commonly known as "hardening of the arteries," P.A.D. occurs when arteries in the legs become narrowed or clogged with fatty deposits, reducing blood flow to the legs. As a result, P.A.D.

Using Atypical Antipsychotics Increases Risk Of Sudden Cardiac Death In Adults
Patients ages 30 to 74 who took atypical antipsychotics such as risperidone (sold as Risperdal), quetiapine (Seroquel), olanzapine (Zyprexa) and clozapine (Clozaril) had a significantly higher risk of sudden death from cardiac arrhythmias and other cardiac causes than patients who did not take these medications, according to a new study funded by HHS' Agency for Healthcare Research and Quality. The risk of death increased with higher doses of the drugs taken.

Few Canadians Aware Of Peripheral Arterial Disease Clogged Arteries In The Legs

Few Canadians Aware Of Peripheral Arterial Disease Clogged Arteries In The Legs
Two out of three Canadians are not aware of peripheral arterial disease (P.A.D.), a common vascular disease that affects as many as 800,000 Canadians, according to a study published in the Canadian Journal of Cardiology. Commonly known as "hardening of the arteries," P.A.D. occurs when arteries in the legs become narrowed or clogged with fatty deposits, reducing blood flow to the legs. As a result, P.A.D.

Using Atypical Antipsychotics Increases Risk Of Sudden Cardiac Death In Adults
Patients ages 30 to 74 who took atypical antipsychotics such as risperidone (sold as Risperdal), quetiapine (Seroquel), olanzapine (Zyprexa) and clozapine (Clozaril) had a significantly higher risk of sudden death from cardiac arrhythmias and other cardiac causes than patients who did not take these medications, according to a new study funded by HHS' Agency for Healthcare Research and Quality. The risk of death increased with higher doses of the drugs taken.

Friday, January 16, 2009

St. Jude Medical Announces Japanese Approval Of Atlas II ICD

St. Jude Medical, Inc. (NYSE:STJ) today announced regulatory approval from the Japanese Ministry of Health, Labour and Welfare (MHLW), in addition to reimbursement approval, of its Atlas® II implantable cardioverter defibrillator (ICD), a device used to treat patients with potentially lethal abnormal heart rhythms. More at...

St. Jude Medical, Inc. (NYSE:STJ) announced the publication of results from the landmark FAME (Fractional flow reserve (FFR) vs. Angiography in Multivessel Evaluation) study that demonstrate a statistically significant 30 percent difference in Major Adverse Cardiac Events (MACE) such as death, myocardial infarction and repeat revascularization. More at...

Phoenix, AZ - Zila Pharmaceuticals, Inc., a division of Zila, Inc. (NASDAQ GM: ZILA) and marketer of the ViziLite® Plus with TBlue® system for the early detection of oral abnormalities that could lead to cancer, has been honored with two awards from Hygienetown, the magazine and web community for dental hygienists. More at...

Royal Philips Electronics (NYSE: PHG, AEX: PHI) and Hansen Medical, Inc. (Nasdaq: HNSN) today announced that they have signed joint development and cooperation agreements to co-develop integrated products that may simplify complex cardiac procedures to diagnose and treat irregular heartbeats, also known as arrhythmias. Cardiac arrhythmias can drastically reduce the quality of life and can also lead to serious health risks including heart failure and stroke. More at...

The first patient receiving focal preventive treatment for vulnerable plaque recently underwent a 6-month follow-up examination that revealed successful stabilization of the target plaque. The interventional cardiology team led by Professor Patrick W. Serruys, MD, PhD, of Erasmus University, placed a vProtect(TM) Luminal Shield in the left anterior descending (LAD) coronary artery of the patient at Erasmus Medical Center in Rotterdam in June of 2008. More at...

Hansen Medical, Inc. (NASDAQ: HNSN) will showcase its Sensei(R) Robotic Catheter System and the CoHesion(TM) 3-D Visualization Module here at the 14th Annual Boston Atrial Fibrillation Symposium, Jan. 15-17, 2009. The integrated electrophysiology (EP) solution offers physicians a software interface between Hansen Medical's robotic catheter system and St. Jude Medical's EnSite(TM) System advanced mapping technology. More at...

Thursday, January 15, 2009

Midlife Coffee And Tea Drinking And The Risk Of Late Life Dementia

Midlife Coffee And Tea Drinking And The Risk Of Late Life Dementia
Midlife coffee drinking can decrease the risk of dementia/Alzheimer's disease (AD) later in life. This conclusion is made in a Finnish Cardiovascular Risk Factors, Aging and Dementia (CAIDE) Study published in the January 2009 issue of the Journal of Alzheimer's Disease (Volume 16:1). This study has been conducted at the University of Kuopio, Finland in collaboration with Karolinska Institutet, Stockholm, Sweden, and the National Public Health Institute, Helsinki, Finland.

Lower Risk Of Dementia And Alzheimer's Linked To Midlife Coffee Drinking
Researchers in Finland and Sweden who followed over 1,400 middle-aged people over twenty years, found that those who drank three to five cups of coffee a day in their midlife years were less likely to develop dementia or Alzheimer's disease in old age compared with those who drank either no coffee at all or very little.

Technology With A Personality For Dementia Care
The University of Dundee and Balhousie Care Group have formed a unique partnership to create an innovative use of touchscreens and multimedia to enhance the care of people with dementia. The partnership has created a new PhD Studentship within the School of Computing at the University, building on existing research excellence in developing technology to help older people.

A Weighted Communicability Measure Applied To Complex Brain Networks
New magnetic resonance imaging techniques allow brain maps of live humans to be constructed. So scientists can now investigate how neurological disorders, such as Parkinson's disease, Alzheimer's disease and schizophrenia change the wiring in the brain. Crofts and Higham at the University of Strathclyde looked at brain networks of patients who had suffered strokes. They introduced a new concept called `weighted communicability', which measures the way information spreads around the brain.

Wednesday, January 14, 2009

Human Beta Cells Can Be Easily Induced To Replicate, According To Pitt Study In Diabetes

Researchers at the University of Pittsburgh School of Medicine have successfully induced human insulin-producing cells, known as beta cells, to replicate robustly in a living animal, as well as in the lab. The discovery not only could improve models and methods for studying diabetes, but also opens up new possibilities for treating the condition. More at...

Introduced in the 1960s, oral contraceptives have been used by about 80 percent of women in the United States at some point in their lives. More at...

Crucial breakthroughs in the treatment of many common diseases such as diabetes and Parkinson's could be achieved by harnessing a powerful scientific approach called systems biology, according to leading scientists from across Europe. In a Science Policy Briefing released by the European Science Foundation, the scientists provide a detailed strategy for the application of systems biology to medical research over the coming years. More at...

MannKind Corporation (Nasdaq: MNKD) announced successful completion of its trial to demonstrate equivalence of its commercial inhaler to the version of the device that was used in clinical trials to deliver AFRESA(TM), MannKind's ultra rapid acting insulin that recently completed Phase 3 clinical trials. More at...

A benchmarking study published in the Journal of Hospital Medicine evaluated contemporary hospital glycemic management in United States academic medical centers, determining glucose control practices are suboptimal and do not meet current American Diabetes Association (ADA) hospital diabetes care standards. More at...

A new study from the US found that patients with peripheral arterial disease (PAD), which is sometimes accompanied by pain in leg muscles, improved their walking endurance and quality of life by taking part in a treadmill walking exercise that also helped patients who did not have the classic symptoms of pain in the legs. More at...

ARYx Therapeutics, Inc. (NASDAQ:ARYX), a biopharmaceutical company, announced further results from a Phase 2b clinical trial testing the safety and efficacy of its oral anti-arrhythmic therapy, ATI-2042, in patients with atrial fibrillation. This follows the December 18, 2008 press release reporting that ATI-2042 reached statistical significance at its primary end point in the two highest of three doses tested. More at...

Tuesday, January 13, 2009

National Infection Control Conference - Stamping Out Spread Of Deadly Infections In Hospital, UK

National Infection Control Conference - Stamping Out Spread Of Deadly Infections In Hospital, UK
The NHS and UK industry will take a giant leap towards stamping out the spread of deadly infections in hospitals at the National Infection Control Conference on 21 January. For the first time, those on the front line will be able to talk to technical innovators about their needs, their problems and the challenges to be overcome.

Standardized Test Battery To Aid Those With Down Syndrome
Researchers at The University of Arizona are developing a set of standardized tests that could improve the lives of people with Down syndrome. The condition, which occurs once in every approximately 800 to 1,000 live births, is signaled by the presence of an extra 21st chromosome. Those with Down syndrome often have mild to severe developmental disabilities, and other health issues that include heart defects and the early onset of Alzheimer's dementia.

Anthera Completes Enrollment And Dosing Of Varespladib Cardiovascular Trial
Anthera Pharmaceuticals, Inc., a privately held biopharmaceutical company developing anti-inflammatory drugs, announced that it has completed enrollment in its 500 patient FRANCIS (Fewer Recurrent Acute coronary events with Near-term Cardiovascular Inflammation Suppression) clinical trial designed to examine the impact of varespladib (A-002) when administered to patients within 96 hours of an Acute Coronary Syndrome (ACS) event.

BD Announces FDA 510(k) Clearance Of Novel Molecular Assay To Diagnose Clostridium Difficile Infections
BD Diagnostics, a segment of BD (Becton, Dickinson and Company) (NYSE: BDX), announced it has received clearance from the U.S. Food and Drug Administration to market the BD GeneOhm(TM) Cdiff molecular assay for the rapid detection of the Toxin B gene found in toxigenic Clostridium difficile, the bacterial pathogen responsible for Clostridium difficile infection (CDI). It is the first CDI molecular diagnostic that offers sensitivity, simplicity and speed in one test procedure.

Helping To Heal Broken Hearts Using 'Smart Scaffolds'
Imagine new treatments for heart disease or muscle loss that direct the body to repair damaged tissue rather than helping it cope with a weakened condition. That's not hard to do thanks to Canadian researchers, who for the first time, have developed an organic substance that attracts and supports cells necessary for tissue repair and can be directly injected into problem areas. This development, published online in The FASEB Journal (

Researchers Find Roughly Half Of Healthy, Younger Adults Could Be At Risk For Heart Disease
Even younger adults who have few short-term risk factors for heart disease may have a higher risk of developing heart disease over their lifetimes, according to new findings by a UT Southwestern Medical Center researcher. The findings, based on clinical studies and appearing in the Jan.

Study Examines Burden Of Diabetes On U.S. Hospitals

A new study published in Value in Health estimates the extent of hospital admissions for individuals with diabetes and its economic burden in the U.S. The results show that, during 2005, Americans with diabetes had 3.5 times more hospital admissions than those without diabetes. Though only 7 percent of the U.S. population has diabetes, in a study of data from 2005, nearly 22 percent ($171 billion dollars) of hospital charges resulted from treating individuals with the condition. Complete news at...

Patients with dementia and diabetes appear to display a different pattern of injuries in their brains than patients with dementia but without diabetes, according to an article posted online today that will appear in the March print issue of Archives of Neurology, one of the JAMA/Archives journals. "The association between diabetes mellitus and increased risk for dementia in the elderly is well documented," the authors write as background information in the article. Complete news at...

Pre-operative screening of patients for methicillin-resistant staphylococcus aureus (MRSA) may be an effective way to reduce infection rates following otolaryngic surgeries, according to new research published in the January 2009 issue of Otolaryngology - Head and Neck Surgery. The study, conducted by researchers at the Massachusetts Ear & Eye Infirmary, is the first to review otolaryngic procedures, and reviewed the medical records of 420 patients. Complete news at...

Monday, January 12, 2009

Collegium Pharmaceutical Announces FDA Approval Of AllerNaze™, A Nasal Inhaled Steroid For The Treatment Of Allergic Rhinitis

Collegium Pharmaceutical Announces FDA Approval Of AllerNaze™, A Nasal Inhaled Steroid For The Treatment Of Allergic Rhinitis
Collegium Pharmaceutical, Inc., a specialty pharmaceutical company, announced that the U.S. Food and Drug Administration (FDA) has approved AllerNaze™ (triamcinolone acetonide, USP) Nasal Spray, 50 mcg, an aqueous based intranasal steroid indicated for the once daily treatment of nasal symptoms associated with both seasonal allergic rhinitis (SAR) and perennial allergic rhinitis (PAR) in adults and children twelve (12) years of age and older.

National Oncologic PET Registry And Supporting Organizations, Including SNM, Continue To Advocate Cancer Coverage

National Oncologic PET Registry And Supporting Organizations, Including SNM, Continue To Advocate Cancer Coverage
The Centers for Medicare and Medicaid Services (CMS) have released a draft of their proposed positron emission tomography (PET) national coverage determination (NCD). This proposed legislation would allow for reimbursement of PET by the federal government for patients with all types of cancer. The proposed decision expands coverage to include cancer staging and restaging, in addition to initial diagnosis.

A Cell's Inactive State Is Critical For Effectiveness Of Cancer Treatment
A new study sheds light on a little understood biological process called quiescence, which enables blood-forming stem cells to exist in a dormant or inactive state in which they are not growing or dividing. According to the study's findings, researchers identified the genetic pathway used to maintain a cell's quiescence, a state that allows bone marrow cells to escape the lethal effects of standard cancer treatments.

Defining Increased Future Risk For Prostate Cancer: Evidence From A Population Based Screening Cohort
UroToday.com - For men with a relatively low PSA on prostate cancer (CaP) screening, what is their risk on future screening exams of having CaP detected? This question was addressed by Dr. Fritz Schröder and collaborators in the online edition of the Journal of Urology. Their work used the Rotterdam Section of the European Randomized Study of Screening for Prostate Cancer (ERSPC) database.

Hospital First In US To Treat Kidney Tumor With New Device Using Electrical Pulses
On Thursday, January 8, Rhode Island Hospital treated an inoperable kidney tumor using a new technology known as NanoKnife. Damian Dupuy, MD, director of ablation services at Rhode Island Hospital and a national pioneer in ablation treatment, performed the procedure -- the first time it has been used on a kidney tumor in the United States.

Mount Sinai Medical Center Hosts 'Man To Man' Prostate Cancer Education And Support Meetings
There's no question that three of the most terrifying words in the English language are "You have cancer." For a man, add the word "prostate" and the fear factor rises even higher, since prostate cancer is the second leading cause of cancer-related death in men. Dr. David B.

Collegium Pharmaceutical Announces FDA Approval Of AllerNaze™, A Nasal Inhaled Steroid For The Treatment Of Allergic Rhinitis
Collegium Pharmaceutical, Inc., a specialty pharmaceutical company, announced that the U.S. Food and Drug Administration (FDA) has approved AllerNaze™ (triamcinolone acetonide, USP) Nasal Spray, 50 mcg, an aqueous based intranasal steroid indicated for the once daily treatment of nasal symptoms associated with both seasonal allergic rhinitis (SAR) and perennial allergic rhinitis (PAR) in adults and children twelve (12) years of age and older.

Saturday, January 10, 2009

Chances Of Surviving Cardiac Arrest Depend On Where Patients Are Treated

Chances Of Surviving Cardiac Arrest Depend On Where Patients Are Treated
Efforts to fight the toll of cardiac arrest have typically focused on pre-hospital factors -- bystander CPR education and improvement, public defibrillation programs, and quicker EMS response. But new research from the University of Pennsylvania School of Medicine reveals that the hospital where patients are cared for after being resuscitated plays a key role in their chances of survival following these incidents, which takes the lives of more than 300,000 Americans each year.

Significance Of LVI In TURBT And Cystectomy Specimens On Survival Of Patients With Urothelial Bladder Cancer
UroToday.com - Lymphovascular invasion (LVI) in urothelial cancer has recently gained interest in the urology community. Several papers have been published emphasizing the poor prognostic significance of this finding both on TURBT (transurethral resection of bladder tumor) and cystectomy specimens.

Significance Of LVI In TURBT And Cystectomy Specimens On Survival Of Patients With Urothelial Bladder Cancer

Significance Of LVI In TURBT And Cystectomy Specimens On Survival Of Patients With Urothelial Bladder Cancer
UroToday.com - Lymphovascular invasion (LVI) in urothelial cancer has recently gained interest in the urology community. Several papers have been published emphasizing the poor prognostic significance of this finding both on TURBT (transurethral resection of bladder tumor) and cystectomy specimens.

Adherence To AAP Practice Guidelines For Urinary Tract Infections At Our Teaching Institution
UroToday.com - A study by Dr. Lopa Shah et al. evaluated the adherence to the American Academy of Pediatrics (AAP) practice guidelines for urinary tract infections (UTI). The AAP developed guidelines to better direct clinicians in the workup. This retrospective study evaluated the uniformity of adherence to these guidelines. A total of 104 charts were reviewed, and data were collected based on the parameters outlined by the AAP.

Healthcare Commission Finds Substantial Improvement In Infection Control At Maidstone And Tunbridge Wells NHS Trust
The Healthcare Commission welcomed substantial improvements in infection control at Maidstone and Tunbridge Wells NHS Trust since an investigation by the watchdog in 2007 identified serious failings. An estimated 90 people definitely or probably died as a result of Clostridium difficile, during two outbreaks of the infection at the trust in 2005 and 2006. It is estimated that a further 30 patients definitely or probably died of C. difficile between April 2004 and September 2005.

Evaluation Of The Safety And Efficacy Of Sildenafil Citrate For Erectile Dysfunction In Men With Multiple Sclerosis
UroToday.com - The etiology of multiple sclerosis (MS)-emergent erectile dysfunction (ED) is still matter of debate, since both organic and psychological factors have been implicated. There is an association between sexual dysfunction (SD) and destructive lesions in the pons, in MS patients. Central and peripheral nerves systems play a key role in the erectile process. The innervation of the penis is both autonomic (sympathetic and parasympathetic) and somatic (sensory and motor).

Continued Increase In Measles Cases, UK
1, 217 cases of confirmed measles have been reported to the Health Protection Agency up to the end of November 2008. Dr Mary Ramsay, an immunisation expert at the Health Protection Agency, said: "We are still seeing a continued increase in measles cases across England and Wales. This rise is due to relatively low MMR vaccine uptake over the past decade and there are now a large number of children who are not fully protected with MMR.

Friday, January 9, 2009

Wellcome Trust Awards £4.1 Million To Achoagen For Proprietary Neoglycosides For Treatment Of Multidrug Resistant Gram-negative Bacteria And MRSA

Achaogen, an emerging biopharmaceutical company addressing the issue of multi-drug resistant bacterial infections through the discovery and development of innovative broad-spectrum antibiotics, today announced that it has received a £4.1 million Seeding Drug Discovery award from the Wellcome Trust. Complete news at...

In the January 8, 2008 issue of The New England Journal of Medicine (NEJM), schistosomiasis expert Charles H. King M.D., Professor of International Health at the Center for Global Health and Diseases at Case Western Reserve University School of Medicine concludes global eradication of schistosomiasis is feasible if the current infection control strategy shifts to a proactive, comprehensive elimination strategy. Dr. King supports the community-based trial by Wang et al. Complete news at...

A preclinical study found a new nasal spray vaccine to provide complete protection against a major botulism toxin, according to a study published in the Nature journal Gene Therapy. Botulism is caused by a bacterium, Clostridium botulinum, which produces toxins that cause paralysis and often death, as the muscles that control breathing fail. Out of an average of 145 U.S. Complete news at...

Animal species that sleep for longer do not suffer as much from parasite infestation and have a greater concentration of immune cells in their blood according to a study published in the open-access journal BMC Evolutionary Biology. The question of why we sleep has long puzzled scientists. Complete news at...

Scientists at St. Jude Children's Research Hospital have demonstrated a more effective treatment for bacterial pneumonia following influenza. They found that the antibiotics clindamycin and azithromycin, which kill bacteria by inhibiting their protein synthesis, are more effective than a standard first-line treatment with the "beta-lactam" antibiotic ampicillin, which causes the bacteria to lyse, or burst. Complete news at...

UCB And WILEX To Enter Into Strategic Alliance To Develop UCB's Preclinical Oncology Portfolio

UCB And WILEX To Enter Into Strategic Alliance To Develop UCB's Preclinical Oncology Portfolio
UCB Pharma S.A. (UCB) and WILEX AG, a company specialising in the development of drugs and diagnostic agents for cancer (WILEX), today announced that they have agreed to enter into a strategic partnership. WILEX will acquire world-wide rights to develop UCB's entire preclinical oncology portfolio, comprising two small-molecule programmes and three antibody programmes.

Marshall Edwards, Inc. Granted Investigative New Drug For Triphendiol
Marshall Edwards, Inc. (NASDAQ: MSHL) announced that it has been granted an Investigative New Drug (IND) approval by the United States Food and Drug Administration to undertake clinical studies with triphendiol as a chemosensitising agent in combination with gemcitabine. This approval will enable a Phase Ib study of triphendiol in combination with gemcitabine in patients with unresectable, locally advanced or metastatic pancreatic and bile duct cancers.

Specialty Training Available For Working With Cancer Survivors
Health and fitness professionals certified by the American College of Sports Medicine (ACSM) can now earn additional qualifications geared toward working with cancer survivors, including those currently undergoing treatment. The new cancer specialty certification is available in collaboration with the American Cancer Society (ACS).

Missouri Expands Health Services For Low-Income Women
Missouri has expanded a program to provide state-funded women's health services -- including pelvic exams, cancer screenings and family planning services -- to low-income women without private health insurance, the AP/Washington Examiner reports. The program is available to women ages 18 to 55 with incomes up to 185% of the federal poverty level.

Does Live, Microscopic Imaging Enhance Physician's Ability To Differentiate Cancerous Lesions In The Bile And Pancreatic Ducts
Doctors at the University of Colorado Hospital in Aurora have treated the first patients in a study to confirm whether using Cellvizio®, the world's smallest microscope, with a standard diagnostic procedure will help physicians identify and differentiate pre-cancerous and cancerous lesions in the bile and pancreatic ducts more effectively than the standard method alone.

Why Bladder Cancer Is Deadlier For Some
Bladder cancer is much more likely to be deadly for women and African-Americans, but the reasons long believed to explain the phenomenon account for only part of the differences for such patients compared to their white and male counterparts, according to results published in the Jan. 1 issue of the journal Cancer.

Novel Vaccine Taking Aim At Cancer Cell "Sweet Spot"
Molecules of sugar sitting on the surface of cancer cells are keys to the development of a new vaccine aimed at both treating and stopping the spread of certain types of cancers called carcinomas, which include prostate, breast, ovarian and lung, among others. Armed with a new two-year grant for $600,000 from the Gateway for Cancer Research, an Illinois-based philanthropic foundation, immunologist Alessandra Franco, M.D., Ph.D.

Thursday, January 8, 2009

Heart Valves Implanted Without Open-Heart Surgery

Heart Valves Implanted Without Open-Heart Surgery
An innovative approach for implanting a new aortic heart valve without open-heart surgery is being offered to patients at NewYork-Presbyterian Hospital/Columbia University Medical Center. Known as the PARTNER (Placement of AoRTic traNscathetER valves) trial, this Phase 3 multicenter study is being led by national co-principal investigators Dr. Martin Leon and Dr.

Obesity May Play A Role In Erectile Dysfunction
A new study may be an important motivational tool for obese men to lose weight! According to a study published in The Journal of Sexual Medicine, the official journal of the International Society for Sexual Medicine, obese men with erectile dysfunction (ED) are shown to have low levels of hormones, such as testosterone. A correlation between certain conditions associated with obesity, particularly hypertension, are the most important determinants of obesity-related ED.

Chronic Total Occlusion: 6th International Summit To Be Held Feb. 5-6, 2009 In NYC
WHAT: The Sixth International Chronic Total Occlusion (CTO) Summit is a two-day conference featuring state-of-the-art technologies, research findings and new developments in therapeutic procedures that are essential for interventional cardiologists to optimize procedural success in chronic total coronary occlusions.

PD2i Technology At Core Of Future Platforms For Risk Stratification Of Trauma And Sudden Cardiac Death
David H. Fater, President and CEO of Vicor Technologies, Inc., announced that on December 29, 2008 Vicor Technologies received FDA 510(k) approval (K082709) to market its PD2i Analyzer, permitting immediate commercialization of the technology. Vicor Technologies, Inc. (OTCBB: VCRT) is a development-stage biotechnology company focused on the commercialization of innovative non-invasive diagnostics using its patented, proprietary PD2i algorithm for cardiovascular and trauma use.

Bicycle Seat Design Can Directly Affect A Man's Sexual Function
Long suspected by the 5 million recreational bike riders and sexual medicine experts, bicycle seat design-shorter noseless seats versus the standard protruding nose extended seat-can directly affect a man's sexual function, based on the nation's first prospective study of healthy policemen riding bikes on the job. The study is published in the current issue of the Journal of Sexual Medicine. Dr.

MMWR: Investigation of Patients Treated by an HIV-Infected Cardiothoracic Surgeon --- Israel, 2007
Transmission of human immunodeficiency virus (HIV) from an infected health-care worker to patients is rare (1), with the greatest potential for occurrence during exposure-prone, invasive surgical procedures in which the blood of the health-care worker might come into contact with patients' blood or mucous membranes.

Nose-spray botulism vaccine shown effective

Nose-spray botulism vaccine shown effective

The goal of the botulism nasal spray vaccine is to offer troops better protection from potential bioweapon, safer stockpiling. A preclinical study found a new nasal spray vaccine to provide complete protection against a major botulism toxin, according to a study published today in the Nature journal Gene Therapy.

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Economy Has Utahns Avoiding Cancer Screenings

In these tight economic times, physicians are reporting their patients are delaying routine cancer screenings due to cost. This has officials at the Utah Department of Health (UDOH) and Utah Cancer Action Network (UCAN) concerned, particularly about colon cancer screening.

“Colorectal cancer is the second leading cause of cancer-related death in the United States and Utah,” said Bronwen Calver, UDOH comprehensive cancer coordinator. “It’s alarming that nearly 45 percent of Utahns age 50 and older have never been screened for it.”

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Health Personnel put 60,000 People at Risk for Hepatitis

A new study from the CDC shows that health care personnel, working outside of hospitals, have put 60,000 people at risk for Hepatitis B and C because of failure to follow basic infection control guidelines.

Dr. John Ward, director of CDC′s Division of Viral Hepatitis says, "Thousands of patients are needlessly exposed to viral hepatitis and other preventable diseases in the very places where they should feel protected. No patient should go to their doctor for health care only to leave with a life-threatening disease." He calls the report a "wake-up call".

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Pennsylvania Recognizes January As Cervical Health Awareness Month

As a part of National Cervical Health Awareness Month, Acting Secretary of Health Everette James today reminded women of the importance of cervical cancer prevention and the need for Pap tests.

“Every January as we begin a new year, we want to remind all Pennsylvanians to do what they can to improve their overall health,” said James. “This month, as we observe National Cervical Cancer Month, I want to remind our mothers, sisters, daughters and friends that yearly examinations are the best way to prevent cervical cancer.

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Failures To Follow Infection Practices Increases Patient's Hepatitis B, C Risk

A new study by the Center for Disease Control and Protection (CDC) in the Annuals of Internal Medicine (Jan 6, 2009) notes that in the last decade, more than 60,000 patients in the United States were asked to get tested for hepatitis B virus (HBV) and hepatitis C virus (HCV) because health care personnel in settings outside hospitals failed to follow basic infection control practices.

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A life in pain: new study examines the experiences of older people

It’s debilitating, isolating and can lead to severe depression - yet pain is widely accepted as something to be expected and regarded as ‘normal’ in later life.

Now a new study from The University of Nottingham examines older people’s experiences of pain and how best Government, the NHS and social care agencies can address the issue. The report, Pain in older people: reflections and experiences from an older person’s perspective, aims to highlight the issue of pain in older people by exploring their experiences of living and coping with persistent pain.

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Wednesday, January 7, 2009

Get Fit For Free, UK

Get Fit For Free, UK
If you are one of the many who've resolved to get fitter this year, then this is the one resolution you should try to keep. Only 40% of men and 28% of women take the recommended amount of exercise and according to the British Medical Journal, regular exercise reduces the risk of conditions such as heart disease and Type 2 diabetes by 20 to 30 per cent.

Clioquinol Inhibits Action Of The CLK1 Aging Gene, May Alleviate Alzheimer's
Recent animal studies have shown that clioquinol - an 80-year old drug once used to treat diarrhea and other gastrointestinal disorders - can reverse the progression of Alzheimer's, Parkinson's and Huntington's diseases. Scientists, however, had a variety of theories to attempt to explain how a single compound could have such similar effects on three unrelated neurodegenerative disorders.

Protective Gene Variant Becomes Bad Actor On A High-Fat Diet
New evidence in mice bolsters the notion that a version of a gene earlier shown to protect lean people against weight gain and insulin resistance can have the opposite effect in those who eat a high-fat diet and are heavier, reveals a report in the January 7th issue of the journal Cell Metabolism, a Cell Press publication.

A Protein That Protects Against Alzheimer's?
Research on the mechanisms involved in neurodegenerative diseases such as Alzheimer's, stroke, dementia, Parkinson's and multiple sclerosis, to name a few, has taken a step forward thanks to the work of biological sciences Ph.D. student Sonia Do Carmo, supervised by Professor Eric Rassart of the

Protein Has Pivotal Role In Obesity, Metabolic Syndrome
A protein known to play a role in development and the formation of organs is also an important factor in the control of obesity and diabetes, said researchers from Baylor College of Medicine in a report that appears in the current issue of the journal Cell Metabolism. Drs.

Medtronic Launches Its First Integrated Power Console (IPC™) Platform For Use In Spinal, Cranial, And Ear, Nose, And Throat Surgeries

Medtronic Launches Its First Integrated Power Console (IPC™) Platform For Use In Spinal, Cranial, And Ear, Nose, And Throat Surgeries
Medtronic, Inc. (NYSE: MDT) announced the launch of the Integrated Power Console (IPC™) platform, its first multispecialty surgical power console for use in spinal, cranial, and ear, nose, and throat (ENT) surgeries. The console powers Medtronic's Midas Rex® Legend EHS® and Legend EHS Stylus® drills, used primarily in spinal and cranial applications, and the Straightshot® M4 Microdebrider, Visao,® and Skeeter® drills used in ENT and neurotology procedures.

Height, Obesity Of Black Women Declining

A yet-to-be-released study has found shorter heights among black women born around 1980 compared with those born in the mid-1960s, a disparity that might be linked to obesity among black women, the Washington Post reports. The study -- conducted by John Komlos, a professor at the University of Munich -- looks at the relationship between standards of living and human health and body size.

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Cell Phone Soap Operas Promote Condom Use, HIV Awareness

A new campaign aims to provide women with messages about HIV awareness, safer sex and condom use through a series of 12 soap opera vignettes that can be viewed on a cell phone, the AP/Atlanta Journal-Constitution reports. Rachel Jones, an educator at Rutgers University's College of Nursing, developed the campaign using professional actors and scripts based on focus groups with women in Newark and Jersey City, N.J.

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Amira Announces The Successful Completion Of GLP Toxicity Studies For A Novel DP2 Antagonist
Amira Pharmaceuticals, Inc. announced AM211, Amira's internally discovered oral drug candidate for the treatment and control of inflammatory and allergic diseases linked to the arachidonic acid pathway, is on target for submission of an IND to the U.S. Food and Drug Administration (FDA) by mid-2009 following the successful completion of Good Laboratory Practices (GLP) toxicity studies.

Low-Carb Diets Prove Better At Controlling Type 2 Diabetes

In a six-month comparison of low-carb diets, one that encourages eating carbohydrates with the lowest-possible rating on the glycemic index leads to greater improvement in blood sugar control, according to Duke University Medical Center researchers.

Patients who followed the no-glycemic diet experienced more frequent reductions, and in some cases elimination, of their need for medication to control type 2 diabetes, according to lead author Eric Westman, MD, director of Duke's Lifestyle Medicine Program. The findings are published online in Nutrition and Metabolism.

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Kentucky Nursing Home Rating System Enhances Tools For Consumers

The Centers for Medicaid and Medicare Services (CMS) recently launched a new rating system to be used as a tool for consumers to access information about the past performances of every CMS certified nursing home in the country, including facilities in Kentucky. The feature is part of CMS’ Nursing Home Compare Web site.

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Tuesday, January 6, 2009

Viagra May Prevent And Improve Heart Failure

Viagra May Prevent And Improve Heart Failure

Researchers at Johns Hopkins find that the erectile dysfunction drug Viagra may prevent and improve heart failure, following studies performed on animal models. The study is the first to show that Viagra (sildenafil) may protect the heart from the ravages of high blood pressure, and improve changes that take place in the heart muscle leading to heart failure.

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FDA Approvals For Sterile Vancomycin HCl USP, 500 Mg/Vial; 1 G/Vial And Sterile Vancomycin HCl USP, 5 G/Vial Pharmacy Bulk Package
Akorn-Strides, LLC announced that the U.S. Food and Drug Administration has granted approvals for two Abbreviated New Drug Applications (ANDAs) for Sterile Vancomycin HCl USP, 500 mg/vial, 1 g/vial and Sterile Vancomycin HCl USP, 5 g/vial Pharmacy Bulk Package. Akorn-Strides, LLC is a Joint Venture that was formed in 2004 by Akorn, Inc. (NASDAQ: AKRX) and Strides Arcolab Limited (NSE: STAR) (BSE: 532531).

Discovery Of Uncultured Bacteria In Amniotic Fluids Of Women Who Experience Preterm Births
Researchers from Case Western Reserve University and Yale University have made a significant advancement in understanding the cause behind why some pregnant women suffer from inflammations in the inner womb without any signs of an infection.

Giant Food To Offer Generic Antibiotics At No Cost For Three Months
Giant Food stores and stores of its sister chain Stop & Shop will provide no-cost generic antibiotics to customers with prescriptions for three months beginning Jan. 2, the Washington Post reports.

Offspring Benefit From Disease Clues During Pregnancy
When there is a threat of disease during pregnancy, mothers produce less aggressive sons with more efficient immune systems, researchers at The University of Nottingham have discovered. The study provides the first evidence for a transgenerational effect on immune response based on environmental cues - with maternal perception of disease risk in the immediate environment potentially determining offspring disease resistance and social dominance.

DiFUSION To Mitigate Surgical Site Infections That Affect An Estimated 780,000 Patients In The USA Each Year
DiFUSION Technologies, Inc., a medical device company targeting the orthopaedic market, today announced its corporate launch. The company will focus on reducing the rising incidence of Surgical Site Infections (SSIs) in spinal surgeries. "In large studies, five out of 100 spine cases result in SSIs often leading to second surgeries that are extremely costly and difficult for the patient," said Dr.

News From The Annals Of Internal Medicine Jan. 6, 2009
1. Outbreaks of Viral Hepatitis Linked to Lapses in Infection Control Practices in Health Care Settings While transmission of Hepatitis B (HBV) and Hepatitis C (HCV) virus in health care settings is considered rare, recent reports of outbreaks indicate a growing problem. Over the past decade, there have been 33 outbreaks in nonhospital health care settings in the United States.

Cytomegalovirus: Cell Death May Bring New Life To Treatment Of Retinal Disease
Just days after the first retinal cell gets infected with the common cytomegalovirus, contiguous cells start committing suicide and researchers believe their death may provide clues to better treatment of this potentially blinding infection. Understanding the cell death may also provide new insight into the larger issue of how the retina responds to assault, whether by infection or a disease process such as diabetes, said Dr.

Monday, January 5, 2009

HIV/AIDS Surveillance Supplemental Report: Enhanced Perinatal Surveillance--Participating Areas in the United States and Dependent Areas, 2000-2003

The HIV/AIDS Surveillance Supplemental Report is published by the Division of HIV/AIDS Prevention, National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention, Coordinating Center for Infectious Diseases, Centers for Disease Control and Prevention (CDC), U.S. Department of Health and Human Services, Atlanta, Georgia. Data are presented for cases of HIV infection among pregnant women reported to CDC through June 2007. More at...

Saturday, January 3, 2009

A New Light On The Anti-tumor Mechanisms Of Scutellaria Barbata

A New Light On The Anti-tumor Mechanisms Of Scutellaria Barbata
Medicinal plants have been used as traditional remedies for hundreds of years. Among them, S. barbata has been traditionally used in treatment of hepatitis, inflammation, osteomyelitis and gynecological diseases in China. Studies indicate that extracts from S. barbata have growth inhibitory effects on a number of human cancers. Reports are available on the treatment of lung, breast and digestive system cancer, hepatoma, and chorioepithelioma with S. barbata extracts.

Cyclophilin B Is A Possible New Target For Treating Breast Cancer
Dr. Charles Clevenger and colleagues at Northwestern University have uncovered that cyclophilin B may contribute to progression in breast cancer. Their report can be found in the January 2009 issue of The American Journal of Pathology. The protein cyclophilin B affects cell division, motility, and death, all of which are altered in cancerous cells. To explore the role of cyclophilin B-mediated gene regulation in breast cancer, Dr.

Inflammation Contributes To Colon Cancer
Researchers led by Dr. Brian Iritani at The University of Washington found that mice that lack the immune inhibitory molecule Smad3 are acutely sensitive to both bacterially-induced inflammation and cancer. They report these findings in the January 2009 issue of The American Journal of Pathology. Bacteria contribute to the development of certain cancers, in some measure, by stimulating chronic inflammation.

Two Compounds In The Trofex™ Prostate Cancer Molecular Imaging Program Specifically Target Prostate Cancer Cells
Molecular Insight Pharmaceuticals, Inc. (NASDAQ: MIPI) announced today the publication of a preclinical study describing the synthesis and initial evaluation of two series of radiolabeled small molecules that target prostate-specific membrane antigen (PSMA), a validated molecular marker for prostate cancer.

In Lung Cancer, Silencing One Crucial Gene Disrupts Normal Functioning Of Genome
While examining patterns of DNA modification in lung cancer, a team of international researchers has discovered what they say is a surprising new mechanism. They say that "silencing" of a single gene in lung cancer led to a general impairment in genome-wide changes in cells, contributing to cancer development and progression.

Fat Tissue Is Sensitive To Irradiation
Researchers led by Dr. Béatrice Cousin at Institut Louis Bugnard found that irradiation damages fat tissue. They report their findings in the January 2009 issue of The American Journal of Pathology. Radiation therapy directed at cancer management also damages normal tissues.

Why Prostate Cancer Patients Fail Hormone Deprivation Therapy
The hormone deprivation therapy that prostate cancer patients often take gives them only a temporary fix, with tumors usually regaining their hold within a couple of years. Now, researchers at Johns Hopkins have discovered critical differences in the hormone receptors on prostate cancer cells in patients who no longer respond to this therapy. The findings, reported in the Jan.

Replacing Old Blood With New Increases The Odds For Survival, TAU Researchers Find
"New blood" can revitalize a company or a sports team. Recent research by Tel Aviv University finds that young blood does a body good as well, especially when it comes to fighting cancer. The TAU researchers, led by Prof.

Friday, January 2, 2009

Innovative Gene Therapy Approach To Prevent Amputations In Patients Suffering Severe Peripheral Artery Disease

Innovative Gene Therapy Approach To Prevent Amputations In Patients Suffering Severe Peripheral Artery Disease
Cardiologists at Rush University Medical Center are studying an investigational medication to prevent amputations in patients suffering the most severe form of peripheral arterial disease. The study involves use of a highly innovative gene therapy approach to promote new blood vessel growth in the legs of patients with critical limb ischemia.

Expanding Festive Waistlines Put Thousands At Risk Of Type 2 Diabetes
Over-indulgence in too many calorific treats such as mince pies (around 200 calories each), Christmas cake (approximately 250 calories per slice) and mulled wine (about 250 calories in a glass) can leave us all struggling to buckle our belts in the New Year. Having a large waist means you are up to eleven times more likely to develop Type 2 diabetes and being overweight or obese is one of the strongest risk factors for developing Type 2 diabetes.

Andromeda Biotech Announces Successful Phase III Interim Results Of Its Lead Product, DiaPep277 For Type 1 Diabetes
Andromeda Biotech, a subsidiary of Clal Biotechnology Industries (CBI), focused on the development of innovative treatment for autoimmune diabetes announces positive results following the Phase III interim analysis for the company's lead product, DiaPep277 for the treatment of Type 1 diabetes.

100,000 People With Diabetes Call '999' A Year
People with diabetes made more than 100,000 emergency calls in the UK last year, according to Diabetes UK. The charity warns that although the ambulance service has recently experienced an unprecedented volume of calls with many for non-emergency situations, most calls from people with diabetes are for severe hypoglycaemia (hypo).

SciClone Announces First Patient Enrolled In Phase 2 Clinical Trial Using SCV-07 To Prevent Oral Mucositis

SciClone Announces First Patient Enrolled In Phase 2 Clinical Trial Using SCV-07 To Prevent Oral Mucositis
SciClone Pharmaceuticals, Inc. (NASDAQ: SCLN) today announced the enrollment of its first patient in its phase 2, multi-center, randomized, double-blind, placebo-controlled study to assess the safety and efficacy of SCV-07 for prevention of oral mucositis (OM) in patients receiving radio-chemotherapy for the treatment of head and neck cancer.

Thursday, January 1, 2009

Nothing To Sneeze At: Real-time Pollen Forecasts - Journal Analytical Chemistry

Nothing To Sneeze At: Real-time Pollen Forecasts - Journal Analytical Chemistry
Researchers in Germany are reporting an advance toward development of technology that could make life easier for millions of people allergic to plant pollen. It could underpin the first automated, real-time systems for identifying specific kinds of allergy-inducing plant pollen circulating in the air. Their study is in the current issue of ACS' Analytical Chemistry, a semi-monthly journal.

NY City Health Department Launches Effort To Study Neighborhood Air Quality
The Health Department today announced the launch of the New York City Community Air Survey, the first comprehensive effort to monitor street level air pollution in neighborhoods across the five boroughs. Air pollution monitors mounted on 150 light posts throughout the city will be used to measure major air pollutants that contribute to health problems.

Sucampo Initiates Phase 1 Study Of SPL-017 For Peripheral Arterial Disease

Sucampo Pharma, Ltd., of Japan, a wholly-owned subsidiary of Sucampo Pharmaceuticals, Inc. (NASDAQ:SCMP), today announced that it has initiated dosing in a first-in-human clinical safety study of a proprietary prostone, SPL-017, as a potential treatment for peripheral arterial disease (PAD). The randomized, double-blind, placebo-controlled, single-center, single ascending dose study will evaluate the safety and pharmacokinetic profile of SPL-017. Complete news at...

Researchers in Germany are reporting an advance toward development of technology that could make life easier for millions of people allergic to plant pollen. It could underpin the first automated, real-time systems for identifying specific kinds of allergy-inducing plant pollen circulating in the air. Their study is in the current issue of ACS' Analytical Chemistry, a semi-monthly journal. Complete news at...