Monday, December 1, 2008

Plumbagin, A Medicinal Plant-Derived Naphthoquinone, Is A Novel Inhibitor Of The Growth And Invasion Of Hormone-Refractory Prostate Cancer

UroToday.com - Dr. Moammir Aziz and colleagues from the University of Wisconsin reported in the November 1, 2008 issue of Cancer Research that plumbagin, a medicinal plant derived naphthoquinone, inhibits castration-resistant prostate cancer (CaP) growth and invasion. Plumbagin was isolated from the roots of plumbago zeylannica L. (Chitrak), which has been used in Indian medicine for thousands of years. Read more ...

UroToday.com - Accurate molecular markers for targeted therapy that correlate with traditional clinical outcomes are not common. An online article from a distinguished group of researchers demonstrates how useful this approach may be. As background, the combination of platelet-derived growth factor receptor (PDGFR) inhibition and taxane chemotherapy for CaP patients with bone metastasis has not demonstrated improved progression-free survival or overall survival benefit. Read more ...

Diabetes and endocrinology specialists at Leighton Hospital in Crewe and Victoria Infirmary, Northwich, can access a summary of the patient's primary care record, enabling them to make more informed decisions at the point of care and helping them to advise a greater number of patients. Read more ...

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