A New Light On The Anti-tumor Mechanisms Of Scutellaria Barbata

A New Light On The Anti-tumor Mechanisms Of Scutellaria Barbata
Medicinal plants have been used as traditional remedies for hundreds of years. Among them, S. barbata has been traditionally used in treatment of hepatitis, inflammation, osteomyelitis and gynecological diseases in China. Studies indicate that extracts from S. barbata have growth inhibitory effects on a number of human cancers. Reports are available on the treatment of lung, breast and digestive system cancer, hepatoma, and chorioepithelioma with S. barbata extracts.

Cyclophilin B Is A Possible New Target For Treating Breast Cancer
Dr. Charles Clevenger and colleagues at Northwestern University have uncovered that cyclophilin B may contribute to progression in breast cancer. Their report can be found in the January 2009 issue of The American Journal of Pathology. The protein cyclophilin B affects cell division, motility, and death, all of which are altered in cancerous cells. To explore the role of cyclophilin B-mediated gene regulation in breast cancer, Dr.

Inflammation Contributes To Colon Cancer
Researchers led by Dr. Brian Iritani at The University of Washington found that mice that lack the immune inhibitory molecule Smad3 are acutely sensitive to both bacterially-induced inflammation and cancer. They report these findings in the January 2009 issue of The American Journal of Pathology. Bacteria contribute to the development of certain cancers, in some measure, by stimulating chronic inflammation.

Two Compounds In The Trofex™ Prostate Cancer Molecular Imaging Program Specifically Target Prostate Cancer Cells
Molecular Insight Pharmaceuticals, Inc. (NASDAQ: MIPI) announced today the publication of a preclinical study describing the synthesis and initial evaluation of two series of radiolabeled small molecules that target prostate-specific membrane antigen (PSMA), a validated molecular marker for prostate cancer.

In Lung Cancer, Silencing One Crucial Gene Disrupts Normal Functioning Of Genome
While examining patterns of DNA modification in lung cancer, a team of international researchers has discovered what they say is a surprising new mechanism. They say that "silencing" of a single gene in lung cancer led to a general impairment in genome-wide changes in cells, contributing to cancer development and progression.

Fat Tissue Is Sensitive To Irradiation
Researchers led by Dr. Béatrice Cousin at Institut Louis Bugnard found that irradiation damages fat tissue. They report their findings in the January 2009 issue of The American Journal of Pathology. Radiation therapy directed at cancer management also damages normal tissues.

Why Prostate Cancer Patients Fail Hormone Deprivation Therapy
The hormone deprivation therapy that prostate cancer patients often take gives them only a temporary fix, with tumors usually regaining their hold within a couple of years. Now, researchers at Johns Hopkins have discovered critical differences in the hormone receptors on prostate cancer cells in patients who no longer respond to this therapy. The findings, reported in the Jan.

Replacing Old Blood With New Increases The Odds For Survival, TAU Researchers Find
"New blood" can revitalize a company or a sports team. Recent research by Tel Aviv University finds that young blood does a body good as well, especially when it comes to fighting cancer. The TAU researchers, led by Prof.