Wistar Scientists Find Key To Keeping Killer T Cells In Prime Shape For Fighting Infection, Cancer

Wistar Scientists Find Key To Keeping Killer T Cells In Prime Shape For Fighting Infection, Cancer
Like tuning a violin to produce strong, elegant notes, researchers at The Wistar Institute have found multiple receptors on the outside of the body's killer immune system cells which they believe can be selectively targeted to keep the cells in superb infection- and disease-fighting condition.

Harnessing MiRNA Natural Gene Repressors For Anticancer Therapy
Michel Sadelain and colleagues, at Memorial Sloan-Kettering Cancer Center, New York, have developed a new approach to modulate the expression of genes for therapeutic purposes, and used this to mediate effective anticancer therapy in mice. Small, noncoding RNA molecules known as miRNAs are powerful natural repressors of gene expression.

Genaera Begins Phase 1b Trial Of Trodusquemine (MSI-1436) In Overweight And Obese Type 2 Diabetics
Genaera Corporation (Nasdaq: GENR) announced that dosing of subjects has begun in study MSI-1436C-102 (Study 102), the multiple ascending dose Phase 1b study of trodusquemine (MSI-1436) in overweight and obese type 2 diabetics. MSI-1436 is a novel therapeutic for the treatment of type 2 diabetes and obesity which works centrally and peripherally to regulate insulin and leptin pathways through the highly selective inhibition of its novel target enzyme, PTP-1B.

Study Demonstrates The Benefit Of Using Chemoradiotherapy In Elderly Patients With Locally Advanced Oesophageal Cancer
Chemoradiotherapy (CRT) can be considered an "effective" treatment for elderly patients with locally advanced oesophageal cancer, reports the British Journal of Cancer. The French study, involving 109 consecutive patients with oesophageal cancer, suggests that characterising patients first with the "Charlson" score may provide useful criteria for deciding which subjects are suitable for treatment.

Nationwide Study Confirms PET As The Most Powerful Imaging Tool In Cancer Management
With the most recent release of data from the National Oncologic PET Registry (NOPR), researchers may have reached the moment of critical mass by confirming the effectiveness of positron emission tomography (PET) in the monitoring of tumor activity across a wide range of cancers.